Working…
COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC: https://www.coronavirus.gov.

Get the latest research information from NIH: https://www.nih.gov/coronavirus.
ClinicalTrials.gov
ClinicalTrials.gov Menu

Supragingival Plaque Removal With and Without Dentifrice

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01986972
Recruitment Status : Completed
First Posted : November 19, 2013
Last Update Posted : November 19, 2013
Sponsor:
Information provided by (Responsible Party):
Raquel Pippi Antoniazzi, Franciscan University Center

Brief Summary:

Purpose: The aim of this study was to compare the efficacy of dental biofilm removal by brushing with and without conventional toothpaste. Settings and Design: Twenty-four students aged 17 to 28 years old participated in this randomized clinical trial.

Materials and Methods: Quadrants 1-3 or 2-4 were randomly allocated to the test group (brushing without dentifrice) or control group (brushing with dentifrice). After 72 hours of cessation of oral hygiene, Quigley & Hein (Turesky) plaque index was assessed before and after brushing by a calibrated and blind examiner. Overtime and intergroup comparisons were performed by paired sample t test.


Condition or disease Intervention/treatment Phase
Dental Plaque Other: Toothbrushing With Dentifrice Other: Toothbrushing Without Dentifrice Phase 2

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 24 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Prevention
Official Title: Supragingival Plaque Removal With and Without Dentifrice: A Randomized Controlled Trial
Study Start Date : July 2009
Actual Primary Completion Date : September 2010
Actual Study Completion Date : November 2010

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Dental Health

Arm Intervention/treatment
Active Comparator: Toothbrushing With Dentifrice
After 72 hours of absence oral hygiene, patients performed toothbrushing with common dentifrice.
Other: Toothbrushing With Dentifrice
The participants were instructed to interrupt any chemical and/or mechanical oral hygiene procedure for 72 hours. Dental plaque was stained by a 2% erithrosin solution, followed by a mouth rinsing with water for 1 minute. Next, the set of dental quadrants (1-3 and 2-4) were randomly allocated to experimental groups by the flip of a coin. One of the sets was brushed with multi bristle brush without the use of dentifrice and the second set was brushed with multi bristle brush using dentifrice. Toothbrushing was performed by the individual's regular technique timed. Two minutes was used for each set. After toothbrushing, the dental biofilm was again stained and evaluated by the same examiner, who was blind to the quadrants brushed with or without dentifrice.
Other Names:
  • Brushed with multi bristle brush
  • Dentifrice closeUp

Experimental: Toothbrushing Without Dentifrice
After 72 hours of absence oral hygiene, patients performed toothbrushing without dentifrice.
Other: Toothbrushing Without Dentifrice
The participants were instructed to interrupt any chemical and/or mechanical oral hygiene procedure for 72 hours. Then, dental plaque was stained by a 2% erithrosin solution, followed by a mouth rinsing with water for 1 minute. Next, the set of dental quadrants (1-3 and 2-4) were randomly allocated to experimental groups by the flip of a coin. One of the sets was brushed with multi bristle brush without the use of dentifrice and the second set was brushed with multi bristle brush using dentifrice. Toothbrushing was performed by the individual's regular technique timed. Two minutes was used for each set. After toothbrushing, the dental biofilm was again stained and evaluated by the same examiner, who was blind to the quadrants brushed with or without dentifrice.




Primary Outcome Measures :
  1. Dental plaque [ Time Frame: Three days ]
    The presence of plaque was determined by Quigley and Hein (QH) (19) modified by Turesky index.



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   17 Years to 28 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • students of both genders systemically healthy.

Exclusion Criteria:

  • individuals who exhibited gingivitis (presence of gingival bleeding at any site);
  • probing depth > 3mm and/or attachment loss >3mm at any site;
  • using orthodontic appliance devices, dental prostheses, dental implants;
  • presence of abrasions, restorations and/or carious lesions at cervical region;
  • individuals who had less than 20 natural teeth.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01986972


Locations
Layout table for location information
Brazil
School of Dentistry, Franciscan University Center
Santa Maria, Rio Grande do Sul, Brazil, 97010-491
Sponsors and Collaborators
Franciscan University Center
Layout table for additonal information
Responsible Party: Raquel Pippi Antoniazzi, Supragingival Plaque Removal With and Without Dentifrice: A Randomized Controlled Trial, Franciscan University Center
ClinicalTrials.gov Identifier: NCT01986972    
Other Study ID Numbers: RAntoniazzi
First Posted: November 19, 2013    Key Record Dates
Last Update Posted: November 19, 2013
Last Verified: November 2013
Keywords provided by Raquel Pippi Antoniazzi, Franciscan University Center:
Toothbrushing
Dental plaque
Dentifrice
Oral hygiene
Additional relevant MeSH terms:
Layout table for MeSH terms
Dental Plaque
Dental Deposits
Tooth Diseases
Stomatognathic Diseases