Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia
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|ClinicalTrials.gov Identifier: NCT01966796|
Recruitment Status : Completed
First Posted : October 22, 2013
Last Update Posted : October 22, 2013
Background The prediction of multi-drug resistant (MDR) pathogens is a key issue in the management of health-care associated pneumonia (HCAP). Multiple risk factors have been proposed, some of which overlap with items of the pneumonia severity index (PSI). The aim of this study was to investigate the relationship between PSI and presence of MDR pathogens.
Methods Patients who were admitted to a tertiary-care hospital from January 2005 to December 2010 were screened by a discharge diagnosis of pneumonia. Patients were enrolled if they fulfilled the definition of HCAP by 2005 ATS/IDSA guideline.
|Condition or disease|
|Healthcare Associated Pneumonia|
MDR bacteria were defined as Pseudomonas aeruginosa (P. aeruginosa), Enterobacter species, those not sensitive to second and third generation cephalosporins, Acinetobacter species, extended-spectrum β-lactamase (ESBL) Enterobacteriaceae such as Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae), Burkholderia cepacia (B. cepacia), Stenotrophomonas maltophilia (S. maltophilia), and methicillin resistant Staphylococcus aureus (MRSA).
The criteria for HCAP is defined as follows: patients who had been hospitalized in an acute care hospital for two or more days within the past 90 days; residents of a nursing home or long-term care facility; recipients of recent intravenous antibiotic therapy, chemotherapy or wound care within the past 30 days; or patients who attended a hospital or hemodialysis clinic.
|Study Type :||Observational|
|Actual Enrollment :||530 participants|
|Official Title:||Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia|
|Study Start Date :||February 2013|
|Actual Primary Completion Date :||October 2013|
|Actual Study Completion Date :||October 2013|
PSI less than 70 or equal to 70
PSI more than 130
- pathogens of healthcare associated pneumonia [ Time Frame: upto seven days ]sputum culture and sterile specimen such as blood or pleural effusion culture for healthcare associated pneumonia within seven days of admission
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01966796
|Far Eastern Memorial Hospital|
|New Taipei, Taiwan, 220|
|Principal Investigator:||Ping-huai Wang, M.D.||Far Eastern Memorial Hospital|