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German Lactat Clearance in Severe Sepsis (GLASS)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01929772
Recruitment Status : Completed
First Posted : August 28, 2013
Last Update Posted : September 23, 2015
Sponsor:
Information provided by (Responsible Party):
RWTH Aachen University

Brief Summary:
The aim of this study is to investigate if there is a correlation between lactate clearance and the course at patients with severe sepsis and septic shock at german intensive care units.

Condition or disease
Severe Sepsis Septic Shock

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Study Type : Observational
Actual Enrollment : 300 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: German Lactat Clearance in Severe Sepsis
Study Start Date : September 2012
Actual Primary Completion Date : April 2015
Actual Study Completion Date : April 2015

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Sepsis Shock

Group/Cohort
severe sepsis or septic shock
patients with severe sepsis or septic shock



Primary Outcome Measures :
  1. Lactate Clearance [ Time Frame: Within 6 hours after diagnoses ]
    Determination of lactate clearance within 6 hours after diagnosis of severe sepisis and septic shocik


Secondary Outcome Measures :
  1. SOFA Score [ Time Frame: Day of hospitalization, day 7, day 8 ]

Other Outcome Measures:
  1. Mortality [ Time Frame: After 28 days ]
    Determination of the mortality of the collective after 28 days

  2. Duration intensive care unit and hospitalization [ Time Frame: 28 days ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with severe sepsis or septic shock
Criteria

Inclusion Criteria:

  • Patients with severe sepsis or septic shock
  • signed informed consent

Exclusion Criteria:

  • severe sepsis or septic schock within 4 weeks before inclusion of study
  • shock of other genesis
  • persons being accomondated in an institution because of court or official order
  • persons being interdependet to the investigator
  • employees of the investigator

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01929772


Locations
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Germany
Department for Operative Intensive Care and Intermediate Care - University Hospital Aachen
Aachen, North Rhine Westfalia, Germany, 52074
Sponsors and Collaborators
RWTH Aachen University
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Responsible Party: RWTH Aachen University
ClinicalTrials.gov Identifier: NCT01929772    
Other Study ID Numbers: 12-052
First Posted: August 28, 2013    Key Record Dates
Last Update Posted: September 23, 2015
Last Verified: September 2015
Additional relevant MeSH terms:
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Sepsis
Toxemia
Infection
Systemic Inflammatory Response Syndrome
Inflammation
Pathologic Processes