COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01929525
Recruitment Status : Unknown
Verified August 2013 by M.Umit UGURLU, Marmara University.
Recruitment status was:  Recruiting
First Posted : August 28, 2013
Last Update Posted : August 28, 2013
Information provided by (Responsible Party):
M.Umit UGURLU, Marmara University

Brief Summary:
Effectiveness of silver nitrate solution in treatment of anal fistula is is aimed to be investigated.

Condition or disease
Anal Fistula

Detailed Description:
The anal fistula is a granulation tissue-lined tract, we thought of a way to ablate this granulation tissue using a chemical agent, which would eventually induce healing with fibrosis and closure of the tract without any surgical intervention. Aiming to reduce the surgery related complications; we investigated the effectiveness of silver nitrate solution as a chemical agent in the treatment of anal fistula.

Layout table for study information
Study Type : Observational
Estimated Enrollment : 70 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Effectiveness of Silver Nitrate Solution in the Treatment of Anal Fistula: A Novel Strategy for Managing Anal Fistula
Study Start Date : August 2013
Estimated Primary Completion Date : January 2014
Estimated Study Completion Date : March 2014

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Fistulas

Silver Nitrate
Irrigation of fistula tract with 1% silver nitrate solution for all patients who accepts the study and signed the written informed consent form.

Primary Outcome Measures :
  1. Number of anal fistula patients treated with silver nitrate solution. [ Time Frame: 1 year ]
    The primary end point in the study was to assess the efficacy of the silver nitrate in the treatment of anal fistula. The number of anal fistula patients who are treated with silver nitrate solution will be calculated. The role of silver nitrate solution in anal fistula treatment will be investigated

Secondary Outcome Measures :
  1. Therapeutic factors [ Time Frame: 1 year ]
    The secondary end point was to identify the clinical and therapeutic factors that significantly affect the primary endpoint.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 80 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with the diagnosis of anal fistula

Inclusion Criteria:

All patients with the diagnosis of anal fistula Patients with recurrence

Exclusion Criteria:

Patients who do not sign the informed consent

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01929525

Layout table for location information
MarmaraUSM Recruiting
Istanbul, Turkey, 34893
Contact: M.Unit Ugurlu, MD    +905324108010   
Sub-Investigator: M.Umit Ugurlu, MD         
Sponsors and Collaborators
Marmara University
Layout table for investigator information
Study Chair: S.CUMHUR YEGEN, MD Marmara University
Layout table for additonal information
Responsible Party: M.Umit UGURLU, Assistant profesor of surgery, Marmara University Identifier: NCT01929525    
Other Study ID Numbers: MarmaraUSM
First Posted: August 28, 2013    Key Record Dates
Last Update Posted: August 28, 2013
Last Verified: August 2013
Additional relevant MeSH terms:
Layout table for MeSH terms
Rectal Fistula
Pathological Conditions, Anatomical
Intestinal Fistula
Digestive System Fistula
Digestive System Diseases
Intestinal Diseases
Gastrointestinal Diseases
Rectal Diseases