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Body Composition in Preschool Children

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ClinicalTrials.gov Identifier: NCT01920724
Recruitment Status : Completed
First Posted : August 12, 2013
Last Update Posted : August 12, 2013
Sponsor:
Collaborator:
International Atomic Energy Agency
Information provided by (Responsible Party):
Mahidol University

Brief Summary:
Thailand has been facing with the double burden of malnutrition. Many studies in Thailand, which aim to explore the situation, causes, and strategies to prevent obesity, have focused on adults, adolescents, or school-aged children. Few studies have been conducted in preschool children. Obesity or stunting during childhood increases the risk of being obesity in adulthood and leads to chronic diseases. If obesity is established in adulthood, it is difficult to reduce the excess weight. Thus, the prevention of obesity or stunting in young children should be highly considered. Study of dietary pattern and reliable field methods to measure fat mass (FM) in children may partly contribute to primary prevention of childhood obesity. The deuterium dilution technique is an accurate and suitable method for children and population-based studies. However, it has not been widely used in children in Thailand. Hence, this study aimed to utilize the deuterium dilution technique for assessing body composition and to determine the quality and quantity of dietary intake among children 3-5 years of age with different nutritional status. We conducted a cross-sectional study in 15 daycare centers in Nakhon Pathom and Samut Prakarn provinces. 120 preschoolers were purposively selected according to their nutritional status: stunted, thin, normal, and overweight/obese. Anthropometric measurements were conducted. Body composition was determined based on total body water using deuterium dilution technique. Dietary intake data were obtained using 2-day 24 hr recall.We hypothesized that stunted and obese children will have more fat mass compared to the normal children.

Condition or disease
Obesity Wasting

Detailed Description:

Body composition of the children was assessed using the deuterium technique. Total body water (TBW) content was calculated. Then, fat free mass (FFM) and fat mass (FM) was calculated.

Weight and height of all children were using a standard technique. Body mass index and nutritional status was calculated using World Health Organization (WHO) growth standard for children 0-5 years.

Dietary intake of children was assessed using 2 non-consecutive 24 hour dietary recalls. The 1st and 2nd recall was about 2 weeks apart. Nutrient intake was calculated using the INMUCAL-Nutrients WD. 4.0 (Institute of Nutrition, 2010).


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Study Type : Observational
Actual Enrollment : 137 participants
Time Perspective: Cross-Sectional
Official Title: Body Composition and Dietary Intake in Preschool Children Aged 3-5 Years in Daycare Centers
Study Start Date : November 2010
Actual Primary Completion Date : July 2012
Actual Study Completion Date : July 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Toddler Health

Group/Cohort
wasting, obesity, stunting, normal
wasting (BMI for age Z-scores < -2 SD), normal (-1 SD ≤ BMI for age Z-scores ≤ +1 SD), obesity (BMI for age Z-scores > +2 SD), and stunting (HAZ < -2 SD).



Primary Outcome Measures :
  1. Body composition [ Time Frame: 4 months ]
    Body fatness


Secondary Outcome Measures :
  1. Nutrient intake [ Time Frame: 4 months ]
    24 hr recall was perform on a weekend day and a weekday day and nutrient intake was calculated.


Biospecimen Retention:   Samples Without DNA
Urine samples


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Ages Eligible for Study:   3 Years to 5 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Children in the daycare centers in Nakhon Pathom and Samut Prakarn porvinces will be screened and categorized into 4 groups, including wasting (BMI for age Z-scores < -2 SD), normal (-1 SD ≤ BMI for age Z-scores ≤ +1 SD), obesity (BMI for age Z-scores > +2 SD), and stunting (HAZ < -2 SD). Then, they will be randomly selected to participate in this study.
Criteria

Inclusion Criteria:

  • Healthy children
  • Aged 3-5 years
  • BMI or HAZ fall in the study protocol

Exclusion Criteria:

  • Chronic diseases
  • Ongoing medical treatments likely to affect body composition
  • Malformation or muscle diseases

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01920724


Locations
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Thailand
Institute of Nutrition, Mahidol University
Phuttamonthon, Nakhon Pathom, Thailand, 73170
Sponsors and Collaborators
Mahidol University
International Atomic Energy Agency
Investigators
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Principal Investigator: Tippawan Pongcharoen, Ph.D. Mahidol University

Additional Information:
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Responsible Party: Mahidol University
ClinicalTrials.gov Identifier: NCT01920724     History of Changes
Other Study ID Numbers: MU-IRB 2010/211.0807
A09/2554 ( Other Grant/Funding Number: Mahidol University )
First Posted: August 12, 2013    Key Record Dates
Last Update Posted: August 12, 2013
Last Verified: August 2013

Keywords provided by Mahidol University:
Preschool children
Body composition