High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome
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|ClinicalTrials.gov Identifier: NCT01919281|
Recruitment Status : Completed
First Posted : August 8, 2013
Last Update Posted : September 29, 2015
The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic Ovary Syndrome (PCOS).
Few studies have examined the effect of strength training alone on insulin sensitivity, reproductive outcomes and body composition in women with PCOS. Most previous studies on aerobic exercise in PCOS have applied moderate exercise intensity.
|Condition or disease||Intervention/treatment||Phase|
|Polycystic Ovary Syndrome||Behavioral: strength training Behavioral: interval training||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||31 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome. A Randomized Controlled Trial|
|Study Start Date :||July 2013|
|Actual Primary Completion Date :||January 2014|
|Actual Study Completion Date :||April 2015|
Experimental: strength training
The subjects will attend for supervised training three sessions per week for 10 weeks (9-12). The strength training program involves dynamic contraction at intensities of 60 - 70 % of 1 repetition maximum (RM) to improve strength and muscle hypertrophy. Each session will contain 8 exercises on the major muscle groups. Each drill consists of 10-12 repetitions (reps) x 3 sets separated by one minute rest between sets.
Behavioral: strength training
Other Name: resistance training
Experimental: interval training
High intensity interval training (HIT) three times per week. The three weekly supervised HIT sessions will include two 4x4 min interval sessions and one 10x1 min session. The HIT consist of "uphill" treadmill running/walking.
Behavioral: interval training
No Intervention: control
Based on the Norwegian recommendation we will encourage the control group to perform 60 minutes of physical activity at moderate to high intensity on a daily basis.
- insulin resistance [ Time Frame: 10 weeks ]measured with the homeostatic model assessment for insulin resistance (HOMA-IR) method
- Body composition [ Time Frame: 10 weeks ]Measured as body fat % on an impedance scale and waist circumference
- Maximum oxygen uptake [ Time Frame: 10 weeks ]Measured during maximum effort exercise test
- Endothelial function [ Time Frame: 10 weeks ]Flow mediated dilatation of the brachial artery.
- Menstruation diary [ Time Frame: up to 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01919281
|Department of circulation and medical imaging , NTNU|
|Trondheim, Norway, 7491|
|Principal Investigator:||Trine Moholdt, phd||Norwegian University of Science and Technology|