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Sevoflurane in Electroconvulsive Therapy

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ClinicalTrials.gov Identifier: NCT01905904
Recruitment Status : Completed
First Posted : July 23, 2013
Last Update Posted : May 16, 2019
Sponsor:
Information provided by (Responsible Party):
Ülkü Özgül, Inonu University

Brief Summary:
The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles

Condition or disease Intervention/treatment Phase
ECT Anesthesia Drug: sevorane Phase 4

Detailed Description:
Motor (EMG) and electroencephalography seizure duration (EEG), heart rate (HR) and mean arterial pressure (MAP) values, and recovery times were recorded.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 25 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Triple (Participant, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: The Comparision of Different Doses of Sevoflurane for Induction of General Anesthesia in Electroconvulsive Therapy
Actual Study Start Date : March 2013
Actual Primary Completion Date : May 2013
Actual Study Completion Date : June 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Seizures
Drug Information available for: Sevoflurane

Arm Intervention/treatment
Active Comparator: sevorane
Sevorane 4% concentration during anesthesia induction
Drug: sevorane
Sevorane 4% Sevorane 7%
Other Name: Sevoflurane

Active Comparator: sevorane %7
Sevorane 7% concentration during anesthesia induction
Drug: sevorane
Sevorane 4% Sevorane 7%
Other Name: Sevoflurane




Primary Outcome Measures :
  1. sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure [ Time Frame: taken prior to the seizure ]

Secondary Outcome Measures :
  1. sevoflurane used in electroconvulsive therapy (ECT) on hemodynamic response. [ Time Frame: taken prior to the seizure ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 60 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Study included 25 patients of American Society of Anesthesiologists (ASA) physical status I-II aged between 18-60 years who were scheduled for ECT sessions under general anesthesia

Exclusion Criteria:

  • Pregnancy
  • Cerebrovascular disease
  • Epilepsy
  • Unstable cardiovascular disease
  • Chronic obstructive pulmonary disease; and
  • Renal or hepatic failure

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01905904


Locations
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Turkey
Inonu Unıversity School of Medicine
Malatya, Turkey, 44100
Sponsors and Collaborators
Inonu University
Investigators
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Principal Investigator: Huseyin Toprak, Professor Inonu University
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Responsible Party: Ülkü Özgül, assistant profesor, Inonu University
ClinicalTrials.gov Identifier: NCT01905904    
Other Study ID Numbers: ulkü_2
First Posted: July 23, 2013    Key Record Dates
Last Update Posted: May 16, 2019
Last Verified: May 2019
Keywords provided by Ülkü Özgül, Inonu University:
electroconvulsive therapy
seizures
sevoflurane
Additional relevant MeSH terms:
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Sevoflurane
Platelet Aggregation Inhibitors
Anesthetics, Inhalation
Anesthetics, General
Anesthetics
Central Nervous System Depressants
Physiological Effects of Drugs