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Juvenile Idiopathic Arthritis in Children in Estonia.

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01905319
Recruitment Status : Completed
First Posted : July 23, 2013
Last Update Posted : March 25, 2020
Information provided by (Responsible Party):
Chris Pruunsild, University of Tartu

Brief Summary:

Aims of the study:

  • to study the incidence rate of juvenile idiopathic arthritis (JIA) and it's clinical subtypes in Estonia for the years 1998-2000;
  • to examine the course and short-term clinical outcome of JIA.

Method: a prospective population-based study carried on in 14 counties of Estonia

Condition or disease Intervention/treatment
Epidemiology Other: Blood collecting for storage of samples

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Study Type : Observational
Actual Enrollment : 162 participants
Observational Model: Ecologic or Community
Time Perspective: Prospective
Official Title: Juvenile Idiopathic Arthritis in Children in Estonia - an Epidemiological and Clinical Investigation.
Study Start Date : January 1998
Actual Primary Completion Date : December 2000
Actual Study Completion Date : December 2002

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
Subsequent new juvenile arthritis cases
During years 1998-2000, all new subsequent cases of juvenile idiopathic arthritis diagnosed in Estonia were included in the study group.
Other: Blood collecting for storage of samples

Primary Outcome Measures :
  1. Mean annual incidence rate of juvenile idiopathic arthritis in Estonia during years 1998-2000. [ Time Frame: 3 years ]

Biospecimen Retention:   Samples Without DNA
Sera and plasma.

Information from the National Library of Medicine

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Ages Eligible for Study:   1 Month to 15 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
During years 1998-2000, 162 newly-diagnosed juvenile idiopathic arthritis cases from 14 counties of Estonia, were included to the study, among them 76 boys and 86 girls.

Inclusion Criteria:

  • The International League of Associations for Rheumatology (ILAR) criteria for juvenile idiopathic arthritis
  • children aged 0-15 years who had arthritis of an unknown cause for at least six weeks with an onset of the disease during the study period

Exclusion Criteria:

  • Children with infectious arthritis, postinfectious arthritis, traumatic arthritis and systemic connective tissue diseases
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Chris Pruunsild, MD, PhD, University of Tartu Identifier: NCT01905319    
Other Study ID Numbers: TARLA 0475;DARLA 0500
First Posted: July 23, 2013    Key Record Dates
Last Update Posted: March 25, 2020
Last Verified: March 2020
Keywords provided by Chris Pruunsild, University of Tartu:
juvenile idiopathic arthritis
incidence rate
Additional relevant MeSH terms:
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Arthritis, Juvenile
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases