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Epipericardial Fat Necrosis: A Misdiagnosed Condition (epipericardial)

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ClinicalTrials.gov Identifier: NCT01903980
Recruitment Status : Completed
First Posted : July 19, 2013
Last Update Posted : July 19, 2013
Sponsor:
Information provided by (Responsible Party):
Karina de Souza Giassi, Hospital Sirio-Libanes

Brief Summary:

Epipericardial fat necrosis is a benign and self-limited condition that mainly curses with acute pleuritic chest pain and therefore must be an important differential diagnosis for patients in emergency department (ED). The knowledge of characteristics symptoms and correct management may avoid misdiagnosis or mistakes with other severe conditions like pulmonary embolism, pericarditis or acute coronary disease.

Despite the importance of this entity, only fewer than 40 cases have been reported since 1957, when the condition was first described.

We have seen a couple of similar cases in our institution during a short period of time, and we suspect that these numbers doesn`t mean the real prevalence of epipericardial fat necrosis, so maybe this condition could be underdiagnosed. Instead, there isn't a study that tried to estimate an incidence of this entity.


Condition or disease Intervention/treatment
Epipericardial Fat Necrosis Other: No intervention. It is a retrospective study

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Study Type : Observational [Patient Registry]
Actual Enrollment : 10 participants
Observational Model: Case-Crossover
Time Perspective: Cross-Sectional
Target Follow-Up Duration: 2 Years
Official Title: Epipericardial Fat Necrosis: A Misdiagnosed Condition
Study Start Date : June 2013
Actual Primary Completion Date : July 2013
Actual Study Completion Date : July 2013

Group/Cohort Intervention/treatment
EFN Cases
Cases of patients with epipericardial fat necrosis CT findings
Other: No intervention. It is a retrospective study
No intervention. It is a retrospective study




Primary Outcome Measures :
  1. Determinate the incidence of epipericardial fat necrosis [ Time Frame: 18 months ]

Secondary Outcome Measures :
  1. Identify misdiagnosed cases of epipericardial fat necrosis [ Time Frame: 18 months ]

Other Outcome Measures:
  1. Describe Clinical and Radiological data of epipericardial fat necrosis [ Time Frame: 18 months ]


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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients from the emergency department of SIrio-Libanes Hospital who performed a chest CT due to any reason
Criteria

Inclusion Criteria:

  • patients with imaging criteria of EFN (defined as a round fat attenuation lesion with peripheral stranding located in the epipericardial fat)

Exclusion Criteria:

  • no exclusion criteria

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01903980


Locations
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Brazil
Hospital Sirio Libanes
Sao paulo, Brazil, 01080050
Hospital Sirio-Libanes
Sao Paulo, Brazil, 01080050
Sponsors and Collaborators
Hospital Sirio-Libanes

Additional Information:
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Responsible Party: Karina de Souza Giassi, MD, Hospital Sirio-Libanes
ClinicalTrials.gov Identifier: NCT01903980     History of Changes
Other Study ID Numbers: Epipericardial Fat Necrosis
Pericardial Necrosis ( Registry Identifier: Epipericardial Fat Necrosis )
First Posted: July 19, 2013    Key Record Dates
Last Update Posted: July 19, 2013
Last Verified: July 2013

Keywords provided by Karina de Souza Giassi, Hospital Sirio-Libanes:
Epipericardial Fat Necrosis
Fat Necrosis
Chest Pain
Pericardial Necrosis
Pleuritic pain

Additional relevant MeSH terms:
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Necrosis
Fat Necrosis
Pathologic Processes