Anti-inflammatory Effect of Aerobic Exercise in Individual With Increased Cardiovascular Risk
|ClinicalTrials.gov Identifier: NCT01903941|
Recruitment Status : Completed
First Posted : July 19, 2013
Last Update Posted : July 19, 2013
|Condition or disease||Intervention/treatment||Phase|
|Inflammation||Behavioral: Aerobic Exercise Behavioral: Only Counseling||Phase 2|
Background: Observational studies suggest that exercise has anti-inflammatory effect, however this idea has not been definitively confirmed by randomized clinical trials.
Objective: To test the hypothesis that aerobic exercise attenuates systemic inflammatory activity in individuals with cardiovascular risk.
Methods: Randomized controlled trial, which included 68 sedentary individuals, with at least two risk factors for coronary heart disease or established cardiovascular disease. The volunteers were randomized to 3 months of supervised aerobic training or just advice when healthy lifestyles. C-reactive protein (CRP) was measured by the method of high sensitivity before and after 3 months of intervention.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||68 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Anti-inflammatory Effect of Aerobic Exercise in Individual With Increased Cardiovascular Risk|
|Study Start Date :||December 2006|
|Actual Primary Completion Date :||April 2008|
|Actual Study Completion Date :||April 2008|
Behavioral: Aerobic Exercise
Placebo Comparator: Control
Behavioral: Only Counseling
- C-reactive protein [ Time Frame: 3 months ]