Repeatability and Reproducibility of the Measurement of Young's Modulus Using Shear Wave Elastography in Volunteers
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|ClinicalTrials.gov Identifier: NCT01903343|
Recruitment Status : Completed
First Posted : July 19, 2013
Last Update Posted : May 8, 2019
|Condition or disease||Intervention/treatment|
|Anesthesia||Device: shear wave elastography|
Shear wave elastography is a quantitative ultrasound modality increasingly used to differentiate between "hard" breast cancer masses and "soft" normal tissue. Unlike strain elastography, shear wave elastography applies a non-compressive longitudinal acoustic radiation force to underlying tissues, inducing transverse shear waves. Studies in Thiel embalmed human cadavers have shown significant differences in Young's modulus between intraneural and extraneural tissue, and ready colour differentiation between tissues.
Therefore, before clinical application, we wish to measure the repeatability and reproducibility of Young's modulus of intraneural and extraneural tissue in volunteers. For measurement, a region of interest (ROI) will be selected over the appropriate nerve and adjacent tissue. The ROI results will be regarded as paired data. Paired data will be measured over and adjacent to the interscalene C5 nerve root, infraclavicular lateral cord, musculocutaneous, median, femoral, saphenous and sciatic nerves.
|Study Type :||Observational|
|Actual Enrollment :||8 participants|
|Official Title:||Repeatability and Reproducibility of the Measurement of Young's Modulus Using Shear Wave Elastography in Volunteers|
|Study Start Date :||October 2014|
|Actual Primary Completion Date :||February 2015|
|Actual Study Completion Date :||February 2015|
Single group of healthy male medical students at Ninewells Hospital & Medical School, Dundee.
Device: shear wave elastography
- To determine the reproducibility of Young's modulus in volunteers using shear wave elastography [ Time Frame: 4 hours ]To determine the reproducibility of Young's modulus in volunteers using shear wave elastography
- To determine the repeatability Young's modulus in volunteers using shear wave elastography [ Time Frame: 4 hours ]To determine the repeatability Young's modulus in volunteers using shear wave elastography
- Video Young's Modulus [ Time Frame: max 2 minutes ]To video changes in tissue stiffness (using the elastography colour map) in concert with changes in the B-Mode image
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01903343
|Department of Anaesthesia, Ninewells Hospital & Medical School|
|Dundee, United Kingdom, DD19SY|
|Principal Investigator:||Graeme A McLeod, MBChB FRCA||NHS Tayside|