VEGF Signaling Promotes Cell Growth and Metastasis in Hepatocellular Carcinoma in a VEGF Receptor Mediated Pathway (HCC)
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|ClinicalTrials.gov Identifier: NCT01892072|
Recruitment Status : Unknown
Verified July 2013 by Ming Kuang,MD,PhD, First Affiliated Hospital, Sun Yat-Sen University.
Recruitment status was: Active, not recruiting
First Posted : July 3, 2013
Last Update Posted : July 11, 2013
|Condition or disease||Intervention/treatment|
|Hepatocellular Carcinoma||Procedure: surgical treatment|
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Observational Model:||Case Control|
|Official Title:||VEGF Signaling Promotes Cell Growth and Metastasis in Hepatocellular Carcinoma in a VEGF Receptor Mediated Pathway|
|Study Start Date :||October 2012|
|Estimated Primary Completion Date :||October 2013|
|Estimated Study Completion Date :||March 2014|
Hepatocellular carcinoma patients treated by surgical treatment
Procedure: surgical treatment
all the patients in the study must have been treated by the surgery at the first time and have been confirmed as 'complete section' by the post-surgery radiological image.
- the variation of the quantity of VEGF signal pathway genes in normal liver tissue,peri tumor,tumor and metastasis. [ Time Frame: the day when conducting surgery (day 1) ]the sections would be collected as previously described.Western blot,immunohistochemistry,PCR would be conducted to find out the variation between the normal liver tissue and tumor,tumor and meta(if have).
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01892072
|First Affiliated Hospital, Sun Yat-Sen University|
|Guangzhou, Guangdong, China, 510000|
|Principal Investigator:||Ming Kuang, MD||First Affiliated Hospital, Sun Yat-Sen University|