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Impact of Exercise Training on Cardiac Function in Man

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ClinicalTrials.gov Identifier: NCT01881139
Recruitment Status : Completed
First Posted : June 19, 2013
Last Update Posted : June 19, 2013
Sponsor:
Information provided by (Responsible Party):
No. 150 Central Hospital of the Chinese People Liberation Army

Brief Summary:
The purpose of this study is to monitor the impact of exercise training on cardiac functions and lipoprotein lipids.

Condition or disease Intervention/treatment Phase
Cardiovascular Disease Behavioral: exercise training Early Phase 1

Detailed Description:
Exercise can increase the mass of left ventricle, which is also called athletic heart. Athletic heart is most frequently encountered as a pathological manifestation of cardiovascular disease, and the early determinants of athelitic remodeling in the general population are largely unknown. We will recruit 45 men aged 18-25 years who will run 5000 meters 2/day for 3 months. caridac function is examined by ECG and echocardiogram, blood pressure, lipoprotein, heart rate, body weight, cardiac troponin will be examined prior to exercise program and 3 months after exercise.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 46 participants
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Health Services Research
Official Title: Effects of Exercise Training on Cardiac Function and Lipid Metabolism in Mem 18-22 Year Old
Study Start Date : December 2012
Actual Primary Completion Date : May 2013
Actual Study Completion Date : May 2013

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: experimental 1
men with exercise training for 3 months
Behavioral: exercise training



Primary Outcome Measures :
  1. change of cardiac function at baseline to exercise training for 3 months [ Time Frame: baseline to 3 months ]

Secondary Outcome Measures :
  1. change of lipoprotein at baseline to exercise training for 3 months [ Time Frame: baseline to 3 months ]
  2. change of heart rate at baseline to exercise training for 3 months [ Time Frame: baseline to 3 months ]
  3. Change of body weight at baseline to exercise training for 3 months [ Time Frame: baseline to 3 months ]
  4. change of cardiac troponin frome baseline to exercise training for 3 months [ Time Frame: baselin to 3 months ]
  5. Change of blood pressure from baseline to exercise training for 3 months [ Time Frame: baseline to 3 months ]


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Ages Eligible for Study:   18 Years to 22 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • men
  • age 18-25 years
  • body mass index (BMI) 18-25 kg/m2
  • no regular exercise
  • no tobacco use
  • no current use of prescribed medications
  • no self-report of acute of chronic diseases

Exclusion Criteria:

  • conditions that do not meet the inclusion criteria listed.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01881139


Locations
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China, Henan
No. 150 Central hospital of Chinese People's Liberation Army
Luoyang, Henan, China, 471000
Sponsors and Collaborators
No. 150 Central Hospital of the Chinese People Liberation Army
Investigators
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Study Director: Shenxu Wang, MD No. 150 Central Hospital of PLA

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Responsible Party: No. 150 Central Hospital of the Chinese People Liberation Army
ClinicalTrials.gov Identifier: NCT01881139     History of Changes
Other Study ID Numbers: 150CTSX002
First Posted: June 19, 2013    Key Record Dates
Last Update Posted: June 19, 2013
Last Verified: June 2013
Keywords provided by No. 150 Central Hospital of the Chinese People Liberation Army:
Exercise
Lipid
Left ventricular
heart function
Additional relevant MeSH terms:
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Cardiovascular Diseases