Identifying Prostate Brachytherapy Seeds Using MRI
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|ClinicalTrials.gov Identifier: NCT01878058|
Recruitment Status : Completed
First Posted : June 14, 2013
Last Update Posted : November 1, 2016
This study will look at the feasibility of using a type of Magnetic Resonance Imaging called Susceptibility Weighted Imaging (SWI) to detect your implanted radioactive seeds. Researchers hope that using SWI will eliminate the need to use CT imaging to detect your implanted radioactive seeds.
This study will also see if the MRI seed detection is as effective as current standard practice of seed detection (routine MRI and CT imaging). This technique would be beneficial for brachytherapy without the need to fuse the MRI and CT images, as is done currently.
|Condition or disease||Intervention/treatment||Phase|
|Prostate Cancer Patients Who Have Brachytherapy Seed Implant||Other: MRI Scan||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||10 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Official Title:||Identifying Prostate Brachytherapy Seeds Using MRI|
|Study Start Date :||October 2012|
|Actual Primary Completion Date :||August 2016|
|Actual Study Completion Date :||August 2016|
Patients will receive an extra MRI scan in addition to their routine scan.
Other: MRI Scan
Patient will receive an additional MRI scan in addition to their standard of care imaging
- Determine if using the MR scan -(SWI) used to detect the implanted radioactive seeds will reduce registration errors [ Time Frame: 6 months ]
- Determine if using the MR scan -(SWI) used to detect the implanted radioactive seeds will reduce planning time for the post-implant plan [ Time Frame: 6 months ]
- Determine if using the MR scan -(SWI) used to detect the implanted radioactive seeds will eliminate the CT scan of the patient. [ Time Frame: 6 months ]
- Compare the differences in MR seed identification using the MR pulse sequence vs. CT images. [ Time Frame: 6 months ]Our goal is to perfectly match these two modalities with acceptance test of 97%. This technique would be beneficial for LDR (Low Dose Rate) Brachytherapy without need to fuse the CT and MR images and eliminate any image registration uncertainly.
- Compare the prostate dosimetry (V100 and D90) in prostate low dose rate therapy using MR alone with CT/MR fusion. [ Time Frame: 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01878058
|University Health Network, The Princess Margaret|
|Toronto, Ontario, Canada, M5G 2M9|
|Principal Investigator:||Saibishkumar Elantholiparameswaran, MD||University Health Network, The Princess Margaret|