A Pilot Study Simulating Multifocal Intraocular Lenses in Healthy Subjects
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|ClinicalTrials.gov Identifier: NCT01873781|
Recruitment Status : Completed
First Posted : June 10, 2013
Last Update Posted : August 29, 2013
Age related cataracts are responsible for about 51 percent of blindness worldwide and according to the WHO affect about 20 million people, according to the WH . As cataract surgery is firstline treatment in the western world, there is a constant attempt to improve artificial intraocular lenes (IOL).
As for this study, the investigators seek to compare four different IOL designs in in a psychophysiological setting, allowing to assess the impact of these IOLs on vision and psychological processing of visual information.
As these IOLs also have downsides, such as reduced light intensity or image alterations, the subjective preference and overall impression shall be investigated. The healthy subjects look through a stable spectacle frame mounted onto a table, which enables the investigator to insert the different IOLs. This would allow subjective testing of IOLs before surgery.
|Condition or disease||Intervention/treatment|
|Lenses, Intraocular Contrast Sensitivity Visual Acuity||Drug: Cyclopentolatehydrochloride|
|Study Type :||Observational|
|Actual Enrollment :||30 participants|
|Study Start Date :||April 2013|
|Actual Primary Completion Date :||July 2013|
|Actual Study Completion Date :||July 2013|
30 healthy male and female subjects
30 healthy male and female subjects aged 18-35
Cyclopentolatehydrochloride 0.5% (Thilo, Alcon, Vienna), dose: 1 drop for study eye
- Eearly Treatment Diabetic Retinopathy Study (ETDRS) visual acuity score [ Time Frame: 1 study day ]To investigate the psychophysiological impact of different optical setups on visual acuity at far, intermediate and near distance.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01873781
|Department of Clinical Pharmacology, Medical University of Vienna|
|Vienna, Austria, 1080|