Influence of FFR on the Clinical Outcome After Percutaneous Coronary Intervention (PERSPECTIVE)
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|ClinicalTrials.gov Identifier: NCT01873560|
Recruitment Status : Completed
First Posted : June 10, 2013
Last Update Posted : March 5, 2019
|Condition or disease|
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||1250 participants|
|Target Follow-Up Duration:||2 Years|
|Official Title:||Influence of Fractional Flow Reserve (FFR) on the Clinical OutcomEs of PERcutaneouS Coronary Intervention (PCI): A ProspECTIVE, Multicenter FFR Registry|
|Study Start Date :||May 2013|
|Actual Primary Completion Date :||June 2016|
|Actual Study Completion Date :||December 2016|
High FFRpost group and low FFRpost group were defined according to the optimal cut-off value for predicting clinical outcome.
- Target-vessel failure [ Time Frame: 2 years after index procedure ]
During two-year follow-up period, target-vessel failure (composite of cardiac death, target-vessel related myocardial infarction, and clinically-driven target vessel revascularization) will be evaluated. Target vessel will be defined as the treated vessel with DES which assessed by post-stent FFR.
All clinical outcome will be reported according to the location of target vessel (LAD vs. non-LAD).
- clinical, angiographic and physiologic predictors for target-vessel failure [ Time Frame: 2 years after index procedure ]Clinical, angiographic and physiologic predictors for target-vessel failure by univariate and multivariate analysis will be performed.
- Intravascular ultrasound (IVUS) derived predictors for post-stent FFR and target vessel failure [ Time Frame: 2 years after index procedure ]In patient who performed IVUS examination, IVUS derived parameters will be evaluated for the prediction of post-stent FFR and target-vessel failure
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01873560
|Korea, Republic of|
|Inje University Ilsan Paik Hospital|
|Goyang, Gyeonggi, Korea, Republic of, 411-706|
|Keimyung University Dongsan Medical Center|
|Daegu, Korea, Republic of|
|Seoul National University Hospital|
|Seoul, Korea, Republic of|
|Ulsan University Hospital|
|Ulsan, Korea, Republic of|
|Principal Investigator:||Joon Hyung Doh, MD, PhD||Inje Univesity Ilsan Paik Hospital|
|Study Director:||Bon-Kwon Koo||Seoul National University Hospital|