Physiological Effects of Deferred Cord Clamping (DoppCord)
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|ClinicalTrials.gov Identifier: NCT01864421|
Recruitment Status : Terminated (New data in public domain suggested continuing study not ethical)
First Posted : May 29, 2013
Last Update Posted : May 17, 2018
|Condition or disease|
|Deferred Umbilical Cord Clamping|
Show Detailed Description
|Study Type :||Observational|
|Actual Enrollment :||15 participants|
|Official Title:||Delivery Room and Postnatal Assessment of the Physiological Effects of Deferred Cord Clamping on the Newborn: A Feasibility Study|
|Study Start Date :||May 2013|
|Actual Primary Completion Date :||May 2018|
|Actual Study Completion Date :||May 2018|
Infants undergoing a deferring of umbilical cord clamping for 30 seconds or more
Immeadiate Cord Clamping
Infants undergoing immediate umbilical cord clamping in the first 20 seconds of life.
- Quantification of blood flow in the umbilical cord or skin [ Time Frame: For Doppler the umbilical cord will be scanned until it is clamped (up to 3 minutes). Blood flow to the skin will be measured for up to 20 minutes as long as this is not interfering with normal clinical care. ]The use of either Doppler ultrasound or a photoplethysmographic (PPG) sensor at delivery to measure either blood flow in the umbilical cord or the skin.
- To assess the cardiovascular status of infants undergoing deferred cord clamping in comparison to immediate clamping. [ Time Frame: In the first 3 days after birth. ]A number of markers of cardiovascular status will be measured including central and peripheral capillary refill time using a PPG sensor and by the investigators observation, non-invasive blood pressure, heart rate, haemoglobin and haematocrit.
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01864421
|University Hospitals Nottingham NHS Trust|
|Nottingham, Nottinghamshire, United Kingdom, NG7 2UH|
|Principal Investigator:||Don Sharkey, BMBS PhD||Univeristy of Nottingham|