Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of MUF (MUF)
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|ClinicalTrials.gov Identifier: NCT01864395|
Recruitment Status : Unknown
Verified May 2013 by University of Saskatchewan.
Recruitment status was: Not yet recruiting
First Posted : May 29, 2013
Last Update Posted : May 29, 2013
|Condition or disease||Intervention/treatment||Phase|
|Coronary Artery Disease Anemia||Procedure: Centrifugation Method Procedure: Online MUF Procedure: Offline MUF||Not Applicable|
Show Detailed Description
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||90 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Care Provider)|
|Official Title:||Clinical and Chemical Outcomes Following Cardiac Surgery: The Post-Operative Effects of Modified Ultrafiltration (On-line MUF) and Off-line (MUF)|
|Study Start Date :||July 2013|
|Estimated Primary Completion Date :||July 2014|
|Estimated Study Completion Date :||October 2014|
Experimental: Control (CF)
Centrifugation Method (CF): currently used to separate whole blood into red blood cells (RBCs) and plasma components. The RBCs are washed with normal saline and re-infused into the patient, while the plasma portion is discarded.
Procedure: Centrifugation Method
Currently used to separate whole blood into red blood cells (RBCs) and plasma components. The RBCs are washed with normal saline and re-infused into the patient, while the plasma portion is discarded.
Experimental: Online MUF
Online MUF: hemofilter is used online while the heart-lung machine is connected to the patient.
Procedure: Online MUF
Hemofilter is used online while the heart-lung machine is connected to the patient.
Experimental: Offline MUF
Offline MUF: hemofilter is used offline when the heart-lung machine is not connected to the patient.
Procedure: Offline MUF
Hemofilter is used offline when the heart-lung machine is not connected to the patient.
- Post-Operative Volume of Chest Tube Drainage [ Time Frame: 12 hours ]Our primary outcome variable is the post-operative volume of chest tube drainage.
- Biochemical Variables [ Time Frame: 12 hours ]Biochemical variables include Hb, albumin fibrinogen, and total protein.
- Clinical Variables [ Time Frame: 12 hours ]Clinical variables include volume of allogeneic transfusion, length of stay in ICU, intubation time, and vasoactive inotrope score.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01864395
|Contact: Erick D McNair, PhDfirstname.lastname@example.org|
|Royal University Hospital||Not yet recruiting|
|Saskatoon, Saskatchewan, Canada, S7N 0W8|
|Contact: Erick D McNair, PhD 1-306-222-7403 email@example.com|
|Principal Investigator:||Erick D McNair, PhD||Clinical Assistant Professor, Department of Surgery, Cardiovascular Surgery|