Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

The Medicines Advice Service Evaluation

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT01864239
Recruitment Status : Completed
First Posted : May 29, 2013
Last Update Posted : May 27, 2015
Sponsor:
Collaborator:
Pharmacy2U
Information provided by (Responsible Party):
University College, London

Brief Summary:
The purpose of this study is to find out whether talking to a pharmacist on the telephone can help to support people taking medicine for a long-term condition.

Condition or disease Intervention/treatment Phase
Type 2 Diabetes Hyperlipidemias Other: Medicines Advice Service Not Applicable

Detailed Description:
Non-adherence to medication is common and although some interventions have shown promise in improving adherence, the findings are inconsistent. This randomised controlled trial aims to test the effectiveness of a pharmacy-based telephone intervention compared to usual care on medication adherence and health outcomes in patients taking medicines for a long-term condition.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 677 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: The Medicines Advice Service: A Randomised Controlled Trial of a Pharmacy-based Telephone Intervention to Support Patients Taking Medication for a Long-term Condition
Study Start Date : November 2012
Actual Primary Completion Date : September 2014
Actual Study Completion Date : September 2014

Resource links provided by the National Library of Medicine


Arm Intervention/treatment
Experimental: Patient-centred tailored intervention
Medicines Advice Service
Other: Medicines Advice Service

The intervention consists of:

  1. Telephone consultations with a pharmacist
  2. Follow-up tailored written information
  3. A medicine reminder chart

No Intervention: Control
Usual care



Primary Outcome Measures :
  1. Self-reported medication adherence [ Time Frame: 6 months ]

Secondary Outcome Measures :
  1. Prescription refill adherence [ Time Frame: Baseline, 6 months and 12 months ]
  2. Self-reported medicine-related problems and concerns [ Time Frame: Baseline, 3 months and 6 months ]
    Medicine-related problems and concerns will be assessed in a self-report questionnaire.

  3. Beliefs about Medicines [ Time Frame: Baseline, 3 months and 6 months ]
    Beliefs about medicines will be assessed in a self-report questionnaire using the Beliefs About Medicines Questionnaire (BMQ) (Horne et al. 1999).

  4. HbA1c [ Time Frame: Baseline and 6 months ]
  5. Serum Cholesterol Levels [ Time Frame: Baseline and 6 months ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients prescribed medication(s) for at least one of the following conditions: type 2 diabetes, hyperlipidemia

Exclusion Criteria:

  • Patients living outside of England
  • Patients with no access to a telephone
  • Patients under the age of 18
  • Patients unable to give written informed consent
  • Patients on drugs for dementia
  • Patients showing signs of dementia or cognitive impairment in conversation
  • Patients with substantial hearing or sight impairment
  • Patients whose medications are ordered by a caregiver/family member
  • Patients with insufficient English to take part in the telephone intervention
  • Patients living with someone already taking part in the study
  • Patients newly prescribed a medication for the conditions listed in the inclusion criteria

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01864239


Locations
Layout table for location information
United Kingdom
UCL School of Pharmacy
London, United Kingdom
Sponsors and Collaborators
University College, London
Pharmacy2U
Investigators
Layout table for investigator information
Principal Investigator: Nick Barber UCL School of Pharmacy

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Layout table for additonal information
Responsible Party: University College, London
ClinicalTrials.gov Identifier: NCT01864239     History of Changes
Other Study ID Numbers: 12/0326
First Posted: May 29, 2013    Key Record Dates
Last Update Posted: May 27, 2015
Last Verified: May 2015
Keywords provided by University College, London:
Adherence
Additional relevant MeSH terms:
Layout table for MeSH terms
Hyperlipidemias
Dyslipidemias
Lipid Metabolism Disorders
Metabolic Diseases