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Trial record 19 of 1478 for:    child psychiatry

The Swedish Versions of ADOS and ADI-R: Psychometric Validation

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ClinicalTrials.gov Identifier: NCT01854333
Recruitment Status : Completed
First Posted : May 15, 2013
Last Update Posted : June 24, 2015
Sponsor:
Information provided by (Responsible Party):
Sven Bölte, Karolinska Institutet

Brief Summary:
Autism spectrum disorders (ASD) are early onset chronic conditions coined by deficits in social reciprocity, communication and stereotypic interests and activities. Other functional impairments such as mental retardation, ADHD, known genetic syndromes and epilepsy are frequent coexisting problems. ASD cause considerable suffering for the affected individuals and burden for their families. With an estimated prevalence exceeding 1%, recent population-based studies suggest that ASD are no rare phenomena. Lifetime societal costs for services and support, together with the opportunity costs of lost productivity in a prototypic developed country are estimated SEK 15.6 million for someone with and SEK 10.3 million for a person without co-existing mental retardation. Despite ongoing efforts, no diagnostically informative biomarker has yet been identified for ASD. The development, refinement and evaluation of behavioral assessment tools has therefore been decisive to progress and quality assurance in ASD clinical practice and research. The most widely used and thoroughly evaluated instruments for ASD in international child mental health are the Autism Diagnostic Interview- Revised (ADI-R) and the Autism Diagnostic Observation Schedule (ADOS). The ADI-R and ADOS are deemed highly by the ASD expert community and thus commonly labeled as being the "gold standard" in ASD diagnostics. Although, Swedish translations of the ADI-R and ADOS exist, a Swedish standardization and cross-cultural validation is still lacking, impeding good clinical practice and research prerequisites for ASD in Sweden. The applied project seeks to broadly establish reliability and validity of the Swedish translations of the ADI-R and ADOS in order to enhance evidence-based clinical practice and stimulate internationally competitive ASD research in Sweden.

Condition or disease Intervention/treatment Phase
Autism Spectrum Disorders Other: ADOS module 1-4 or ADI-R Not Applicable

  Show Detailed Description

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 50 participants
Intervention Model: Single Group Assignment
Masking: Single (Investigator)
Primary Purpose: Diagnostic
Official Title: The Swedish Versions of ADOS and ADI-R: Psychometric Validation
Study Start Date : January 2011
Actual Primary Completion Date : October 2014
Actual Study Completion Date : November 2014

Resource links provided by the National Library of Medicine

Drug Information available for: Adenosine

Arm Intervention/treatment
ADOS module 1-4, ADI-R
Individuals recruited within clinical services in child psychiatry and child medicine in Stockholm county and Lund for whom assessments with ADOS module 1-4 or ADI-R are appropriate.
Other: ADOS module 1-4 or ADI-R



Primary Outcome Measures :
  1. Diagnosis of Autism Spectrum Disorders [ Time Frame: The avarege time frame between the ADOS/ADI-R assessment and the final assessment of clinical diagnosis is one month. ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

None

Exclusion Criteria:

None


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01854333


Locations
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Sweden
Karolinska Institute Center for Neurodevelopmental Disorders
Stockholm, Stockholms län, Sweden, 113 35
Sponsors and Collaborators
Karolinska Institutet
Investigators
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Principal Investigator: Sven Bölte, Professor, PhD Karolinska Institute Center for Neurodevelomental Disorders

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Responsible Party: Sven Bölte, Professor, PhD, Karolinska Institutet
ClinicalTrials.gov Identifier: NCT01854333     History of Changes
Other Study ID Numbers: EvaluationADOS&ADI-R
First Posted: May 15, 2013    Key Record Dates
Last Update Posted: June 24, 2015
Last Verified: June 2015

Keywords provided by Sven Bölte, Karolinska Institutet:
Diagnostics
ADOS
ADI-R
Psychometrics
Autism spectrum disorders
Autism

Additional relevant MeSH terms:
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Autism Spectrum Disorder
Child Development Disorders, Pervasive
Neurodevelopmental Disorders
Mental Disorders