Optimizing Continuous-flow Left Ventricular Assist Device Settings and Identification of Pump Malfunction - A Comparative Study of Echocardiography and Invasive Hemodynamics
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|ClinicalTrials.gov Identifier: NCT01851889|
Recruitment Status : Completed
First Posted : May 13, 2013
Last Update Posted : October 28, 2015
The purpose of the trial is to identify factors which can be used as guidance when optimizing continuous-flow left ventricular assist device (CF-LVAD) settings.
The hypothesis of the study is that pulmonary capillary wedge pressure (PCWP) will change independently of left ventricular end diastolic diameter (LVEDD) when increasing pump speed ie ΔPCWP/RPM ≠ ΔLVEDD/RPM.
The primary combined endpoint of the study is correlation between ΔPCWP and LVEDD slope under ramp testing in a cohort of "continuous-flow left ventricular assist device" heart failure patients.
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||15 participants|
|Study Start Date :||April 2013|
|Primary Completion Date :||December 2013|
|Study Completion Date :||October 2015|
|CF-LVAD pump speed.|
- Pulmonary capillary wedge pressure in mmHg. [ Time Frame: On trial day. ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01851889
|University Hospital Rigshospitalet.|
|Copenhagen, Kbh Oe, Denmark, 2100|
|Principal Investigator:||Mette H Jung, MD||Department of Cardiology B, University Hospital Rigshospitalet.|
|Principal Investigator:||Finn Gustafsson, MD, DMSc, PhD||Department of Cardiology B, University Hospital Rigshospitalet.|