Assessment of Coronary Artery Disease in Stroke Patients (ACADIS)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01850693|
Recruitment Status : Completed
First Posted : May 9, 2013
Last Update Posted : November 10, 2015
|Condition or disease|
|Coronary Artery Disease|
Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.
Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.
Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||1657 participants|
|Target Follow-Up Duration:||5 Years|
|Official Title:||Prevalence and Characteristics of Coronary Atherosclerosis in Stroke Patients Using Coronary CT Angiography|
|Study Start Date :||July 2006|
|Actual Primary Completion Date :||December 2012|
|Actual Study Completion Date :||June 2015|
Coronary artery disease, Stroke
Coronary artery disease, stroke, coronary CT angiography
- MACE (Major Adverse Cardiac Event) [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ]MACE was included as follows: 1) all-cause mortality, 2) myocardial infarction, 3) unstable angina requiring hospitalization
- Any cardiac events [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ]1) late revascularization: who underwent revascularization therapy mroe than 90days after CCTA and referral due ot new symptoms or an abnormal function test, 2) heart failure required hospitalization.
- Repeated stroke [ Time Frame: Participants will be followed until June. 2015, an expeded average of 5 years ]newly developed stroke after CCTA scan
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01850693
|Korea, Republic of|
|Seoul National University Bundang Hospital|
|Seongnam-si, Gyeonggi-do, Korea, Republic of, 436-707|
|Principal Investigator:||Eun Ju Chun, MD||Department of Radiology, Seoul National University Bundang Hospital|