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Circulating Tumor Cells (CTCs) in Advanced Gastric Cancer

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01848015
Recruitment Status : Unknown
Verified May 2015 by Shen Lin, Peking University.
Recruitment status was:  Recruiting
First Posted : May 7, 2013
Last Update Posted : May 19, 2015
Information provided by (Responsible Party):
Shen Lin, Peking University

Brief Summary:

To assess the predictive value of circulating tumor cells (CTCs) for recurrence of advanced gastric cancer after radical resection.

To identify the relationship between the detection of circulation tumor cells and recurrence patterns of gastric cancer after radical resection.

Condition or disease Intervention/treatment
Gastric Cancer Other: detection of CTCs

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Study Type : Observational
Estimated Enrollment : 200 participants
Time Perspective: Prospective
Official Title: Prediction of Recurrence in Advanced Gastric Cancer After Radical Resection by Circulating Tumor Cells (CTCs)
Study Start Date : June 2013
Estimated Primary Completion Date : June 2016
Estimated Study Completion Date : June 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Stomach Cancer

Group/Cohort Intervention/treatment
CTCs positive Other: detection of CTCs

Primary Outcome Measures :
  1. CTCs [ Time Frame: 2 months ]

Secondary Outcome Measures :
  1. Recurrence of gastric cancer after radical resection [ Time Frame: 2 years ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years to 75 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
The patients with advanced gastric cancer accepted radical resection(D2)

Inclusion Criteria:

  • Having signed informed consent
  • Age≥ 18 years old
  • Histologically confirmed gastric adenocarcinoma
  • Preoperative clinical examination and imaging indicating operable disease
  • complete resection (R0 resection)
  • D2 or D2+ resection

Exclusion Criteria:

  • Other tumor type than adenocarcinoma
  • Patients who have been given preoperative chemotherapy/chemoradiation.
  • Staging investigations or intraoperative exploration indicating inoperable disease
  • R1 or R2 resection
  • D0 or D1 resection
  • Patients unreliable for follow up
  • Past history of malignancy

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01848015

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Contact: Lin Shen, MD,PhD (86)10-88196175

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China, Beijing
Peking cancer hospital Recruiting
Beijing, Beijing, China, 100142
Contact: Ming Lu, MD    (86)10-88196561   
Sponsors and Collaborators
Peking University
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Principal Investigator: Lin Shen, MD, PhD Peking University
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Shen Lin, Director of GI oncology, Peking University Identifier: NCT01848015    
Other Study ID Numbers: CGOG5003
First Posted: May 7, 2013    Key Record Dates
Last Update Posted: May 19, 2015
Last Verified: May 2015
Keywords provided by Shen Lin, Peking University:
CTCs before and after gastrectomy
Additional relevant MeSH terms:
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Stomach Neoplasms
Neoplastic Cells, Circulating
Gastrointestinal Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Digestive System Diseases
Gastrointestinal Diseases
Stomach Diseases
Neoplasm Metastasis
Neoplastic Processes
Pathologic Processes