Central Venous and Abdominal Pressures and the Inferior Vena Cava
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|ClinicalTrials.gov Identifier: NCT01840670|
Recruitment Status : Unknown
Verified August 2013 by Franco Cavaliere, Catholic University of the Sacred Heart.
Recruitment status was: Recruiting
First Posted : April 26, 2013
Last Update Posted : August 7, 2013
The elliptic shape of inferior vena cava (IVC) sections, while hindering the ultrasound measurement of IVC diameter, may provide a useful tool to estimate central venous pressure (CVP). Hypothetically, the higher is CVP and more the ratio R between minimum and maximum diameters approximates 1. The purpose of this study is to determine R values in four different sections before and after a fluid load test, in order to evaluate if R is affected by the test and at which level the variation is larger.
The secondary endpoint is to search for the parameter best predictive of the positivity of the fluid load test among IVC minimum and maximum diameters, eccentricity, section area, and blood velocity at the level that presented the largest variations after the fluid load.
|Condition or disease||Intervention/treatment|
|Hypovolemia||Drug: Rapid fluid load test|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||16 participants|
|Official Title:||Influence of Central Venous and Abdominal Pressures on the Inferior Vena Cava Shape and Size|
|Study Start Date :||May 2013|
|Estimated Primary Completion Date :||June 2014|
|Estimated Study Completion Date :||June 2014|
- Drug: Rapid fluid load test
The test will be performed by infusing 250-300 mL/m2 Body Surface Area of 6% hydroxyethyl starch 6% 130/0.4 (VoluvenR) in 30 minutesOther Name: VoluvenR
- The eccentricity of inferior vena cava transverse sections [ Time Frame: Baseline and after forty minutes ]The ratio R between the minimum and maximum diameters of inferior vena cava transverse sections at four different levels
- Blood velocity [ Time Frame: Baseline and after forty minutes ]Maximum and average blood velocity measured immediately below the confluence of the hepatic veins by Doppler provided that the angle of insonation is 60° or less.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01840670
|Contact: Franco Cavaliere, Prof.||+39 06 email@example.com|
|Catholic University of the Sacred Heart||Recruiting|
|Rome, Italy, 00168|
|Contact: Franco Cavaliere, Prof. +39 06 30154386 firstname.lastname@example.org|
|Sub-Investigator: Riccardo Gargaruti, MD|
|Principal Investigator: Alessandro Cina, MD|
|Principal Investigator:||Franco Cavaliere, MD||Catholic University of the Sacred Heart|