Effects of the Sugar Sucrose on Bodyweight and Energy Intake Over 28 Days in Obese Women

• ClinicalTrials.gov Identifier: NCT01799096
• Recruitment Status: Completed
• First Posted: February 26, 2013
• Last Update Posted: January 28, 2016
• Sponsor: University of Hull
• Information provided by (Responsible Party): Richard Hammersley, University of Hull

Study Description

Brief Summary:

This study partially replicates two previous studies with normal weight women, and overweight women. Both found that women could compensate for sucrose added to the diet in carbonated soft drinks (4 x250ml total1800 kJ per day) when it was given blind over a period of 4 weeks. The hypothesis is that this applies also to obese women, who will not gain weight, increase overall energy intake in the diet, or eat differently whilst consuming sucrose. 42 participants shall be randomly assigned to either be given carbonated drinks that contain sucrose, or drinks that are artificially sweetened.

Condition or disease	Intervention/treatment	Phase
Obesity	Dietary Supplement: Sucrose; Dietary Supplement: Aspartame	Not Applicable

Study Design

• Study Type: Interventional (Clinical Trial)
• Actual Enrollment: 41 participants
• Allocation: Randomized
• Intervention Model: Parallel Assignment
• Masking: Single (Participant)
• Primary Purpose: Basic Science
• Official Title: Effects of the Sugar Sucrose on Bodyweight and Energy Intake Over 28 Days in Obese Women
• Study Start Date: September 2006
• Actual Primary Completion Date: October 2008
• Actual Study Completion Date: October 2008

Arms and Interventions

Arm	Intervention/treatment
Experimental: Sucrose; Receives sucrose	Dietary Supplement: Sucrose; Sucrose in carbonated soft drinks (4 x250ml total1800 kJ per day); Other Name: Irn Bru
Placebo Comparator: Aspartame; Receives Aspartame sweetened drinks	Dietary Supplement: Aspartame; Intensely sweetened soft drink (no energy content); Other Name: Diet Irn Bru

Outcome Measures

Primary Outcome Measures :

1. Change in body weight from baseline [ Time Frame: 4 weeks ]

Secondary Outcome Measures :

1. Mean daily dietary intake estimated from unweighed food diaries [ Time Frame: 4 weeks ]

Other Outcome Measures:

1. Rated Mood [ Time Frame: 4 weeks ]
   Mood was assessed 4 times per day over the study period

Eligibility Criteria

• Ages Eligible for Study: 20 Years to 55 Years (Adult)
• Sexes Eligible for Study: Female
• Accepts Healthy Volunteers: Yes

Criteria

Inclusion Criteria:

• Female
• BMI 30-35 kg/m²
• at least one period of dietary restriction of 4 weeks or more in the last 24 months

Exclusion Criteria:

• dislike of popular sweet carbonated drinks
• dieting during the last month
• history of diabetes
• having an eating disorder
• depression,
• being a smoker
• pregnant
• lactating,
• wearing a pacemaker
• currently taking medication for mood or thyroid disorders

Contacts and Locations

No Contacts or Locations Provided

More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Reid M, Hammersley R, Duffy M, Ballantyne C. Effects on obese women of the sugar sucrose added to the diet over 28 d: a quasi-randomised, single-blind, controlled trial. Br J Nutr. 2014 Feb;111(3):563-70. doi: 10.1017/S0007114513002687. Epub 2013 Oct 29.

• Responsible Party: Richard Hammersley, Professor of Health Psychology, University of Hull
• ClinicalTrials.gov Identifier: NCT01799096
• Other Study ID Numbers: MRRH003
• First Posted: February 26, 2013
• Last Update Posted: January 28, 2016
• Last Verified: January 2016

Additional relevant MeSH terms:

Body Weight