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Kidney Allograft Recipients in England - an Observational Cohort Study (KARE)

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ClinicalTrials.gov Identifier: NCT01798524
Recruitment Status : Completed
First Posted : February 26, 2013
Last Update Posted : February 26, 2013
Sponsor:
Information provided by (Responsible Party):
Adnan Sharif, University Hospital Birmingham NHS Foundation Trust

Brief Summary:
Kidney transplantation is the renal replacement therapy of choice for the majority of patients with end-stage kidney disease. Epidemiological studies of kidney allograft recipients can aid in the understanding of cause and effect of health and disease post-transplantation. The combination of health care and information technology has made the potential of transplant professionals to use health information effectively crucial to guide kidney transplant management. The aim of this study is to undertake an observational cohort study of kidney allograft recipients, supported by linking analysis across different database sources, to provide a comprehensive biomedical dataset of information.

Condition or disease
Kidney Transplantation

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Study Type : Observational
Actual Enrollment : 19688 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: An Observation Cohort Study of Kidney Allograft Recipients in England by Data Linkage Analysis
Study Start Date : November 2011
Actual Primary Completion Date : February 2013

Resource links provided by the National Library of Medicine


Group/Cohort
Kidney allograft recipients



Primary Outcome Measures :
  1. Mortality within the first year post kidney transplantation [ Time Frame: One year ]

Secondary Outcome Measures :
  1. Mortality beyond the first year post kidney transplantation [ Time Frame: Up to 12 years ]


Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
All kidney allograft recipients transplanted at an English transplant centre between April 2001 and March 2012
Criteria

Inclusion Criteria:

  • Kidney transplant alone
  • English Transplant centre
  • All ages
  • Kidney allograft receipt between April 2001 and March 2012

Exclusion Criteria:

  • Multiple organ transplant
  • Transplant performed at non-English centre

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01798524


Locations
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United Kingdom
University Hospitals Birmingham NHS Foundation trust
Birmingham, United Kingdom, B15 2WB
Sponsors and Collaborators
University Hospital Birmingham NHS Foundation Trust
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Responsible Party: Adnan Sharif, Dr, University Hospital Birmingham NHS Foundation Trust
ClinicalTrials.gov Identifier: NCT01798524    
Other Study ID Numbers: HES-ONS
First Posted: February 26, 2013    Key Record Dates
Last Update Posted: February 26, 2013
Last Verified: February 2013
Keywords provided by Adnan Sharif, University Hospital Birmingham NHS Foundation Trust:
Transplant
Kidney
England