Study of Cartilage Relaxometry and Physical Activity in Osteoarthritis
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT01797679|
Recruitment Status : Withdrawn
First Posted : February 22, 2013
Last Update Posted : October 1, 2013
|Condition or disease||Intervention/treatment||Phase|
|Osteoarthritis||Other: Strength Training Other: Aerobic Exercise||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||0 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||Efficacy of Strength and Aerobic Exercise on the Articular Cartilage of Patients With Mild and Moderate Knee Osteoarthritis Measured by T2 and T1 Rho MR Imaging - A Randomized Controlled Trial|
|Study Start Date :||March 2013|
|Estimated Primary Completion Date :||December 2014|
|Estimated Study Completion Date :||March 2017|
The strength group include progressive strength training and neuromuscular exercises. The inclusion will be performed 2-3 times a week for 12 weeks.
Intervention: Other: Strength training
Other: Strength Training
Experimental: Aerobic exercise
The aerobic exercise group will cycle on an ergometer bicycle 2-3 times a week for 12 weeks on moderate loading. The loading will be controlled by a heart rate monitor and is defined as 85% of maximal heart rate.
Other: Aerobic Exercise
No Intervention: Control Group
The control group will do as usual.
- Qualitative Cartilage Morphology Assessment [ Time Frame: One year ]Indirect cartilage morphology will by assessed by X-ray Direct cartilage morphology will be assessed by MRI morphometry The biochemical composition of the cartilage will be assessed by relaxometry (T2 and T1 rho relaxation times)
- Semiquantitative Cartilage Assessment [ Time Frame: One year ]Using semiquantitative techniques, the clinical manifestations of osteoarthritis assessed by MRI such as: cartilage lesions and bone marrow lesions will be assessed and quantified by MRI.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01797679
|Akershus University Hospital|
|Lorenskog, Norway, 1478|