Determination of Protein Requirements in Pregnancy
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|ClinicalTrials.gov Identifier: NCT01784198|
Recruitment Status : Completed
First Posted : February 5, 2013
Last Update Posted : July 18, 2017
Protein is an essential part of our diet. It is used to build muscle and body tissue, send signals throughout our body and to support the immune system. Dietary protein is even more crucial during pregnancy as it is needed for healthy growth and development of the baby. There is very minimal data available on how much additional protein is required during pregnancy. Current recommendations are based on older techniques such as nitrogen balance studies of non-pregnant adults and minimally based on pregnancy specific data. There is no scientific information regarding the amount of protein needed during different stages of pregnancy.
The investigators hypothesize that the current recommendations of protein intake during pregnancy are underestimated.
The goal of this study is to measure protein requirement in healthy pregnant women (19-35y)using a more quick and modern technique called the indicator amino acid oxidation technique (IAAO).
|Condition or disease||Intervention/treatment||Phase|
|Pregnancy||Dietary Supplement: Protein Intake||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||20 participants|
|Intervention Model:||Single Group Assignment|
|Primary Purpose:||Basic Science|
|Official Title:||Determination of Protein Requirements in Healthy Pregnant Women Using Indicator Amino Acid Oxidation Technique|
|Study Start Date :||April 2011|
|Actual Primary Completion Date :||December 2013|
|Actual Study Completion Date :||March 2014|
Experimental: Protein Intake
Dietary supplement:Protein intake
Dietary Supplement: Protein Intake
Oral consumption of Eight hourly experimental meals- Includes 4 tracer-free experimental meals containing a mixture of free amino acids, calories from a flavored liquid and protein free cookies and 4- labeled amino acid experimental meals.
- 13 Carbon dioxide production [ Time Frame: 8 hours (1 study day) ]Urine and breath samples will be collected during the study to measure the rate of oxidation of tracer in expired breath and flux by enrichment in urine.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01784198
|Canada, British Columbia|
|Child & Family Research Institute|
|Vancouver, British Columbia, Canada, V5Z4H4|
|Principal Investigator:||Rajavel Elango, Ph.D||Child & Family Research Institute/University of British Columbia|