Comparison of the Efficacy of Entecavir and Tenofovir Monotherapy for the Treatment of Nucleos(t)Ide-naïve Patients With Chronic Hepatitis B in Korea
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ClinicalTrials.gov Identifier: NCT01776814
Recruitment Status : Unknown
Verified January 2013 by Ju Seung Kim, MD, Gachon University Gil Medical Center. Recruitment status was: Not yet recruiting
First Posted : January 28, 2013
Last Update Posted : January 28, 2013
Gachon University Gil Medical Center
Information provided by (Responsible Party):
Ju Seung Kim, MD, Gachon University Gil Medical Center
Chronic hepatitis B virus infection is an important cause of morbidity and mortality. Tenofovir disoproxil fumarate and entecavir were licensed for the treatment of hepatitis B virus infection. In this study, the investigators will try to make comparison between Entecavir and Tenofovir and investigate the efficacy.
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 70 Years (Adult, Older Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
treatment of nucleos(t)ide-naive patients who were diagnosed with chronic hepatitis B in Korea
18 < Age < 70
HBV DNA > 100,000 copies/mL and increased ALT over 2 times compared with normal range if HBsAg (+), HBeAg (+)
HBV DNA > 10,000 copies/mL and increased ALT compared with normal range if HBsAg (+), HBeAg (-)