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Cerebral Palsy Hip Health Related Quality of Life

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01773161
Recruitment Status : Completed
First Posted : January 23, 2013
Last Update Posted : January 10, 2018
Information provided by (Responsible Party):
Kishore Mulpuri, University of British Columbia

Brief Summary:
Children with cerebral palsy are at an increased risk of having their hips move partially or completely out of joint. This can cause pain and restrict movement at the hip, making sitting in a wheelchair uncomfortable and make personal care difficult. This condition may be treated with surgery. Surgeons use x-rays taken before and after the surgery to determine whether or not the surgery has been successful. However, it is also important to know whether the surgery has improved life from the child or the caregiver's point of view. The investigators will also evaluate if waiting for surgery affects the child. This information will be added to results from a physical exam and an evaluation of the child's x-rays for a more complete picture of how this surgery impacts the lives of our patients. It is predicted that that the health-related quality of life of children with cerebral palsy will improve following surgery.

Condition or disease Intervention/treatment
Cerebral Palsy Patient Undergoing Hip Surgery Quality of Life Procedure: Cerebral palsy, post hip surgery

Detailed Description:
HRQoL will be measured using the Child Health Index of Life with Disabilities (CPCHILD). Our specific hypothesis is that health related quality of life, as measured by the CPCHILD will change by at least a mean of 10 points from pre- to post-surgery.

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Study Type : Observational
Actual Enrollment : 31 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Health Related Quality of Life in Patients With Cerebral Palsy Undergoing Surgery for Dislocating Hips
Study Start Date : February 2011
Actual Primary Completion Date : December 2017
Actual Study Completion Date : December 2017

Resource links provided by the National Library of Medicine

Group/Cohort Intervention/treatment
Cerebral palsy, post hip surgery
Children between the ages of 4-18 undergoing surgical treatment for hip subluxation or dislocation secondary to cerebral palsy.
Procedure: Cerebral palsy, post hip surgery
All subjects will undergo surgical treatment for hip subluxation or dislocation. HRQoL, radiographic, and clinical data will be measured at multiple time points.

Primary Outcome Measures :
  1. Change in quality of life from pre-op to one year post-op [ Time Frame: Baseline to 1 year post-op ]
    Change in quality of life will be measured by the Caregiver Priorities and Child Health Index of Life with Disabilities questionnaires.

Secondary Outcome Measures :
  1. Changes in variables obtained from physical and radiological examination [ Time Frame: Baseline to 1 year post-op ]

    A physical exam includes: child's range of motion at the hip, true hamstring length, tone, Gross Motor Function Classification System level, functional mobility, and pain.

    Radiological measures include: acetabular index, centre edge angle of Wiberg and shape of head, avascular necrosis of the femoral head, arthritis, pelvic obliquity, Cobb's angle for scoliosis.

Information from the National Library of Medicine

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Ages Eligible for Study:   4 Years to 18 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Children with cerebral palsy who are undergoing surgery for hip subluxation/dislocation at BC Children's Hospital

Inclusion Criteria:

  • Ages 4-18
  • Undergoing surgical treatment for hip subluxation or dislocation
  • Diagnosis of cerebral palsy or similar condition causing motor impairment
  • Consent to participate

Exclusion Criteria:

  • Diagnosis of neuromuscular disorders other than cerebral palsy
  • younger than 4, older than 18
  • Reimer's migration percentage <40%

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01773161

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Canada, British Columbia
British Columbia Children's Hospital
Vancouver, British Columbia, Canada, V6H 3V4
Sponsors and Collaborators
University of British Columbia
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Principal Investigator: Kishore Mulpuri, MBBS, MS, MHSc University of British Columbia
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Responsible Party: Kishore Mulpuri, Principle Investigator, University of British Columbia Identifier: NCT01773161    
Other Study ID Numbers: H10-03210
CW11-0006 ( Other Identifier: Children's and Women's Health Centre of BC (incl. Sunny Hill) )
First Posted: January 23, 2013    Key Record Dates
Last Update Posted: January 10, 2018
Last Verified: January 2018
Keywords provided by Kishore Mulpuri, University of British Columbia:
Cerebral Palsy
Hip surgery
Quality of Life
Additional relevant MeSH terms:
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Cerebral Palsy
Neurologic Manifestations
Nervous System Diseases
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases