Comparison Between Propofol-remifentanil Total Intravenous Anesthesia and Desflurane-remifentanil Balanced Anesthesia With Regard to Post-anesthetic Functional Recovery Measured With QoR-40
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ClinicalTrials.gov Identifier: NCT01760018 |
Recruitment Status :
Completed
First Posted : January 3, 2013
Last Update Posted : February 19, 2014
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Thyroid Operation Under General Anesthesia | Drug: desflurane group Drug: TIVA group | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 76 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | Double (Participant, Investigator) |
Study Start Date : | December 2012 |
Actual Primary Completion Date : | January 2013 |
Actual Study Completion Date : | January 2013 |

Arm | Intervention/treatment |
---|---|
Experimental: Desflurane group |
Drug: desflurane group
anesthesia is maintained with desflurane and remifentanil (Desflurane group) |
Active Comparator: TIVA(total intravenous anesthesia) group |
Drug: TIVA group
anesthesia is maintained with fresofol and remifentanil (TIVA group). |
- QoR-40 score [ Time Frame: at 24 hours later after surgery ]QoR-40 score is going to be measured at preoperative period, 24 hours, and 48 hours later after surgery.

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Ages Eligible for Study: | 20 Years to 65 Years (Adult, Older Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- patients who are undergoing thyroid operation belong to ASA class 1 or 2
Exclusion Criteria:
- patients who are belongs to ASA class 3 or more,
- patients who have underlying complicated cardiovascular or psychological disease.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01760018
Korea, Republic of | |
Severance Hospital | |
Seoul, Korea, Republic of, 120-752 |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Yonsei University |
ClinicalTrials.gov Identifier: | NCT01760018 |
Other Study ID Numbers: |
4-2012-0748 |
First Posted: | January 3, 2013 Key Record Dates |
Last Update Posted: | February 19, 2014 |
Last Verified: | February 2014 |
desflurane, total intravenous anesthesia, QoR-40 |
Desflurane Anesthetics, Inhalation Anesthetics, General |
Anesthetics Central Nervous System Depressants Physiological Effects of Drugs |