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Exercise Intervention and Dexterity in Parkinson

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01749917
Recruitment Status : Completed
First Posted : December 17, 2012
Last Update Posted : November 2, 2016
Information provided by (Responsible Party):
Marie Carmen Valenza, Universidad de Granada

Brief Summary:

The investigators conducted an intervention based in proprioceptive exercises and balance tasks. The investigators also carried out a brief intervention in manual dexterity.

The study hypothesis is that a brief intervention in upper extremities and a exercise program can increase functionality in Parkinson.

Condition or disease Intervention/treatment Phase
Parkinson Other: Exercise program Other: Control intervention Not Applicable

Detailed Description:
Motor symptoms in Parkinson frequently affect upper extremities. This has been associated in previous studies with limitation in the performance of activities of daily living and, consequently, with a decrease in quality of life. The possibility that a brief intervention improves eye-hand dexterity in Parkinson's, may be a therapeutic option to improve the performance of activities of daily living. The investigators also conducted an intervention based in proprioceptive exercises and balance tasks to improve functionality.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 60 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single (Investigator)
Primary Purpose: Treatment
Official Title: Therapeutic Intervention in Motor Disorders in Parkinson.
Study Start Date : December 2012
Actual Primary Completion Date : December 2014
Actual Study Completion Date : February 2015

Resource links provided by the National Library of Medicine

Arm Intervention/treatment
Active Comparator: Control group
30 people are recruited in order to the inclusion criteria for the study. The study include subjects who can complete the assessment battery of tests at the beginning and end in order to perform the control intervention.
Other: Control intervention
Active upper limb range of movement exercises for 15 minutes.

Experimental: Exercise program group
30 people are recruited, diagnosed with Parkinson attending to the Parkinson Association of Granada aged between 40 and 65 years. No sex differences. The study include subjects who can complete the assessment battery of tests at the beginning and end.
Other: Exercise program
Exercise program An brief exercise session including proprioceptive and dexterity activities
Other Name: Plaster of resistance activities

Primary Outcome Measures :
  1. Manual dexterity [ Time Frame: baseline, 6 months ]

    Change from baseline to postintervention in dexterity. This is assessed using the Purdue Pegboard Test.

    The Purdue pegboard test is a timed physical test used to measure manual dexterity. Test subjects are asked to place small pins into holes in the pegboard using a specific hand and following a specific process.

Secondary Outcome Measures :
  1. Grip strength [ Time Frame: baseline, 6 months ]

    Grip strength is measured using a Jamar dynamometer with a standard protocol allowing three attempts on each side. During each measurement, patients were sitting with their shoulder adducted and elbow flexed to 90°. The maximum value achieved from all six attempts was used in analyses.


  2. Pressure pain measure [ Time Frame: baseline, 6 months. ]
    The pressure pain threshold for each site (three points in upper extremities) is assessed using the pressure algometer. All assessments were made by the same investigator. All the subjects were trained to familiarize the subjects with the pressure algometry procedure before the measures in an anatomical site different from the chosen sites for this study.

  3. Nervous assessment [ Time Frame: baseline, 6 months. ]

    Neurodynamic tests are used in upper extremities. It moves most of the nerves between the neck and hand, including the median nerve, radial and ulnar, brachial plexus, spinal nerves and cervical nerve roots.

    The patient is placed supine position. It is measured with a goniometer.

  4. Risk of falls. [ Time Frame: baseline, 6 months. ]
    The risk of falls is measured with the timed up and go. It measures in seconds, the time taken by an individual to stand up from a standard arm chair,walk a distance of 3 meters, turn, walk back to the chair, and sit down.

Information from the National Library of Medicine

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Ages Eligible for Study:   40 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Subjects diagnosed with Parkinson attending to the Parkinson Association of Granada.
  • Subjects who can complete the assessment battery of tests at the beginning and at the end of the study.

Exclusion Criteria:

  • Auditive and visual disturbances.
  • Cognitive problems.
  • Psychiatric pathology.
  • Sensorial disturbances.
  • Traumatic pathology of the hand.
  • Concomitant neurological conditions.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01749917

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Faculty of Health Sciences. University of Granada.
Granada, Andalucia, Spain, 18071
Sponsors and Collaborators
Universidad de Granada
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Principal Investigator: M. Carmen Valenza, PH MD Department of Physical Therapy. University of Granada.

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Responsible Party: Marie Carmen Valenza, Assistant professor, Universidad de Granada Identifier: NCT01749917    
Other Study ID Numbers: DF0036UG
First Posted: December 17, 2012    Key Record Dates
Last Update Posted: November 2, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided
Keywords provided by Marie Carmen Valenza, Universidad de Granada:
Additional relevant MeSH terms:
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Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases