Glucose Metabolism Disorders and Metabolic Syndrome Before and After Primary Hip and Knee Replacement (HyTe-2)
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|ClinicalTrials.gov Identifier: NCT01743313|
Recruitment Status : Suspended (Primary researcher not able to continue research at the moment.)
First Posted : December 6, 2012
Last Update Posted : July 20, 2018
|Condition or disease|
|Hyperglycemia Hypercholesterolemia Persistent Postoperative Pain Hip Replacement Knee Replacement|
|Study Type :||Observational|
|Actual Enrollment :||155 participants|
|Official Title:||Hyperglycemia in Joint Replacement Recipients: Glucose Metabolism Disorders and Metabolic Syndrome in Osteoarthritis Patients Before and After Primary Hip and Knee Replacement|
|Study Start Date :||April 2012|
|Actual Primary Completion Date :||August 2012|
|Estimated Study Completion Date :||June 2019|
Hip and knee replacement recipients
Hip and knee replacement recipients (with osteoarthritis) enrolled previously into "Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement" study (NCT01021826).
- Change in glucose tolerance, measured using oral glucose tolerance test [ Time Frame: Baseline and 12-24 months after surgery ]The patients are grouped into three groups that are evaluated 12, 18 and ca. 24 months after surgery.
- Change in cholesterol levels (HDL, LDL, triglycerides) [ Time Frame: Baseline and 12-24 months after surgery ]
- Pain [ Time Frame: 12-24 months after surgery ]Assessed using visual analog scale. Patients are divided in three groups that are evaluated 12, 18 and 24 months after surgery.
- Change in plasma adipokine and cytokine concentrations [ Time Frame: Baseline and 12-24 months after surgery. ]
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01743313
|Coxa, Hospital for Joint Replacement|
|Tampere, Finland, 33520|
|Study Director:||Esa Jämsen, MD, PhD||Coxa, Hospital for Joint Replacement|