The Genetics Behind Vitamin D Status (VitDgen) (VitDgen)
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|ClinicalTrials.gov Identifier: NCT01741233|
Recruitment Status : Completed
First Posted : December 4, 2012
Last Update Posted : August 1, 2013
The overall purpose of the study is to investigate whether there is a relationship between 26 different single nucleotide polymorphisms (SNPs) in the vitamin D pathway, ultraviolet B (UV-B) irradiation of the skin and vitamin D status.
The hypothesis is that vitamin D status are influated by different genetic genotypes in the vitamin D pathway.
|Condition or disease||Intervention/treatment||Phase|
|Vitamin D Deficiency||Genetic: VitDgen||Not Applicable|
In this study approximately 80 participants (over 18 years) are included. All the participants has previously participated in the VitmaD intervention study (NCT01184716) .
Participants will in total receive 4 times UV-B irradiation (3 SED) with two day apart each time, to stimulate vitamin D production in the skin. The participants skintype will be measured. The study starts in January 2013 and runs to the end of Marts 2013. During this winter period, it is in Denmark not possible to produce vitamin D in the skin through sunlight exposure.
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||102 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||The Genetics Behind Vitamin D Status (VitDgen)|
|Study Start Date :||November 2012|
|Actual Primary Completion Date :||March 2013|
|Actual Study Completion Date :||March 2013|
Experimental: UV-B irraditation
- serum 25-hydroxyvitamin D [ Time Frame: 10 days ]Measures the vitamin D status i serum at baseline and at the end of the project
- Skintest [ Time Frame: 10 days ]Optimize scientific; measures pigmentation and redness of the skin. Are measured at baseline and at end of project
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01741233
|Bispebjerg, Copenhagen, Denmark, 2400|
|DTU / National Food Institute|
|Morkhoj, Søborg, Denmark, 2860|
|Principal Investigator:||Lone Rasmussen, M.Sc., Ph.D.||DTU, Denmark|