Effects of Aging and Aerobic Exercise Training on Brain Glucose Metabolism
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|ClinicalTrials.gov Identifier: NCT01738568|
Recruitment Status : Active, not recruiting
First Posted : November 30, 2012
Last Update Posted : August 13, 2019
|Condition or disease||Intervention/treatment||Phase|
|Dementia||Behavioral: High intensity aerobic training Behavioral: Sedentary Control||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||40 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of Aging and Aerobic Exercise Training on Brain Glucose Metabolism|
|Study Start Date :||October 2012|
|Estimated Primary Completion Date :||June 2021|
|Estimated Study Completion Date :||December 2022|
Behavioral: High intensity aerobic training
High intensity aerobic interval training will be performed 12-weeks. Exercise training will last 1 hour per day, 5 days per week and include high intensity interval cycling at ~70-95% maximum workload for 4 minutes followed by 3 minutes of rest.
Behavioral: Sedentary Control
Sedentary control participants will not perform any regular exercise for 12-weeks.
- Change in Brain Glucose Uptake [ Time Frame: 12 weeks ]The investigators will assess brain glucose uptake using positron emission tomography at baseline and following 12-weeks of either aerobic exercise training or sedentary control period.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01738568
|United States, Minnesota|
|Mayo Clinic in Rochester|
|Rochester, Minnesota, United States, 55905|
|Principal Investigator:||Val Lowe, MD||Mayo Clinic|