COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC) (EAOC)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01732432
Recruitment Status : Withdrawn
First Posted : November 22, 2012
Last Update Posted : April 1, 2015
Information provided by (Responsible Party):
University Hospital, Basel, Switzerland

Brief Summary:
The purpose of this study is to determine whether a relationship exists between a previously established diagnosis of endometriosis and the consecutive risk of developing a clear cell or endometrioid ovarian carcinoma. All histopathological records since 1980 with these diagnoses (endometriosis, clear cell and endometrioid ovarian carcinoma) will be reviewed. Cancer registry data will be assessed to investigate differences in survival of women with endometriosis-associated ovarian carcinomas and those ovarian carcinoma patients without previous diagnosis of endometriosis.

Condition or disease
Endometrioid Carcinoma Clear Cell Carcinoma Endometriosis

Layout table for study information
Study Type : Observational
Actual Enrollment : 0 participants
Time Perspective: Retrospective
Official Title: Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC) - Epidemiological and Molecular Pathological Aspects
Study Start Date : October 2012
Actual Primary Completion Date : August 2013
Actual Study Completion Date : December 2013

Primary Outcome Measures :
  1. incidence and clinical outcome of endometriosis-associated ovarian carcinomas [ Time Frame: 30 years ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   30 Years to 85 Years   (Adult, Older Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
primary care hospital, university hospital

Inclusion Criteria:

  • endometrioid ovarian carcinoma
  • clear cell ovarian carcinoma
  • endometriosis, atypical endometriosis
  • borderline tumors with endometriosis

Exclusion Criteria:

  • undifferentiated carcinomas
  • germ cell tumors
  • sex cord-stromal tumors

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01732432

Sponsors and Collaborators
University Hospital, Basel, Switzerland
Layout table for investigator information
Principal Investigator: Ellen Obermann, MD, Dr. University Hospital Basel, University of Basel
Principal Investigator: Ellen C Obermann, MD Institute of Pathology, University Hospital Basel, University of Basel
Layout table for additonal information
Responsible Party: University Hospital, Basel, Switzerland Identifier: NCT01732432    
Other Study ID Numbers: 210/12
First Posted: November 22, 2012    Key Record Dates
Last Update Posted: April 1, 2015
Last Verified: March 2015
Additional relevant MeSH terms:
Layout table for MeSH terms
Ovarian Neoplasms
Carcinoma, Ovarian Epithelial
Adenocarcinoma, Clear Cell
Carcinoma, Endometrioid
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Endocrine Gland Neoplasms
Neoplasms by Site
Ovarian Diseases
Adnexal Diseases
Genital Neoplasms, Female
Urogenital Neoplasms
Endocrine System Diseases
Gonadal Disorders
Neoplasms, Complex and Mixed
Endometrial Neoplasms
Uterine Neoplasms