Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease
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|ClinicalTrials.gov Identifier: NCT01686984|
Recruitment Status : Completed
First Posted : September 18, 2012
Last Update Posted : May 14, 2015
The purpose of this study is to investigate how inspiratory flow pattern influences CO2 elimination in people without primary lung disease.
The hypothesis is that a long mean distribution time, caused by a long postinspiratory pause and high end-inspiratory flow, will promote CO2 exchange in the alveoli.
|Condition or disease||Intervention/treatment||Phase|
|Pulmonary Gas Exchange Carbon Dioxide||Other: Altered breath||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||8 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Influence of Inspiratory Flow Pattern on Exchange of Carbon Dioxide in Humans Without Primary Lung Disease|
|Study Start Date :||September 2012|
|Actual Primary Completion Date :||May 2015|
|Actual Study Completion Date :||May 2015|
Experimental: Altered breath
The group where the investigators alter the inspiratory and expiratory aspects of a ventilated breath.
Other: Altered breath
- Carbon dioxide elimination in a ventilator assisted breath. [ Time Frame: 30 minutes ]
- Blood CO2 concentration. [ Time Frame: 30 minutes ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01686984
|Division of Brain, Heart and Lungs, Neurosurgical Clinic, Skane University Hospital, Lund|
|Lund, Skane, Sweden, 22185|
|Principal Investigator:||Mikael Bodelsson, Professor||Division of Anesthesia, Skane University Hospital, Lund, Sweden|