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Comparison of ECMO Use and Conventional Treatment in Adults With Septic Shock

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ClinicalTrials.gov Identifier: NCT01685112
Recruitment Status : Unknown
Verified September 2012 by National Taiwan University Hospital.
Recruitment status was:  Recruiting
First Posted : September 13, 2012
Last Update Posted : October 12, 2012
Sponsor:
Information provided by (Responsible Party):
National Taiwan University Hospital

Brief Summary:
Although few cases reported successful treatment of septic shock using extracorporeal membrane oxygenation (ECMO) in adults, no studies compared ECMO to conventional treatment (without ECMO) as treatment for adults with septic shock. Since it is difficult to conduct a randomized study to allocate patients in such critical condition, we aimed to conduct a retrospective observational study using propensity score matched analysis to compare the survival of adults with septic shock treated by ECMO or conventional treatment.

Condition or disease
Septic Shock

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Study Type : Observational
Estimated Enrollment : 300 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Comparison of ECMO Use and Conventional Treatment in Adults With Septic Shock
Study Start Date : September 2012
Estimated Primary Completion Date : August 2013
Estimated Study Completion Date : August 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Shock

Group/Cohort
Conventional Group
Patients who developed refractory shock, but didn't received ECMO as salvage treatment
ECMO group
Patient who have septic shock, and progreseed to have ECMO as salvage therapy



Primary Outcome Measures :
  1. In hospital mortality [ Time Frame: 30 days ]
    inhospital mortality as primary outcome, mean length of hospital stay around 30 days



Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Adults patient who admitted to ICU and had severe sepsis and progressed to septic shock
Criteria

Inclusion Criteria:

  • age >20
  • admitted at ICU
  • septic shock

Exclusion Criteria:

  • nil

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01685112


Contacts
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Contact: YuChung Chuang, MD 886-972652532 weischuang@gmail.com

Locations
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Taiwan
National Taiwan University Hospital Recruiting
Taipei, Taiwan, 100
Contact: YuChung Chuang, MD    886-972652532    weischuang@gmail.com   
Principal Investigator: YuChung Chuang, MD         
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
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Principal Investigator: YuChung Chuang, MD National Taiwan University Hospital

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Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT01685112    
Other Study ID Numbers: 201207079RIC
First Posted: September 13, 2012    Key Record Dates
Last Update Posted: October 12, 2012
Last Verified: September 2012
Keywords provided by National Taiwan University Hospital:
adults
ECMO
Additional relevant MeSH terms:
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Shock, Septic
Shock
Pathologic Processes
Sepsis
Infection
Systemic Inflammatory Response Syndrome
Inflammation