Study the Effect of Oral Zinc Supplementation on Enzymes of Nitric Oxide Pathway
![]() |
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
ClinicalTrials.gov Identifier: NCT01684059 |
Recruitment Status :
Completed
First Posted : September 12, 2012
Last Update Posted : September 12, 2012
|
- Study Details
- Tabular View
- No Results Posted
- Disclaimer
- How to Read a Study Record
Condition or disease | Intervention/treatment |
---|---|
Asthenozoospermia | Dietary Supplement: zinc sulfate |
Study Type : | Observational |
Actual Enrollment : | 60 participants |
Observational Model: | Case-Control |
Time Perspective: | Retrospective |
Official Title: | Study the Effect of Oral Zinc Supplementation on Enzymes of Nitric Oxide Pathway |
Study Start Date : | July 2011 |
Actual Primary Completion Date : | July 2012 |
Actual Study Completion Date : | July 2012 |

Group/Cohort | Intervention/treatment |
---|---|
Single group
Single group: each participant receive same intervention (zinc sulfate) throughout study (non-randomized)
|
Dietary Supplement: zinc sulfate
every participant took two capsules of zinc sulfate per day for three months (each one 220mg) |
- Nitric oxide synthase activity [ Time Frame: at the end of three months ]
- Arginase activity [ Time Frame: at the end of three months ]

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study: | 27 Years to 35 Years (Adult) |
Sexes Eligible for Study: | Male |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- the presence of asthenozoospermia in the semen sample.
Exclusion Criteria:
- the absence of endocrinopathy,
- varicocele, and
- female factor infertility. Smokers and alcoholic men were excluded from the study because of their recognized high seminal ROS levels and decreased antioxidant levels

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01684059
Iraq | |
Babylon university/ college of science | |
Hilla, Iraq, IQ |
Principal Investigator: | mahmoud H. hadwan, phD | babylon university / Iraq | |
Study Chair: | Lamia A. Almashhedy, phD | Babylon university/Iraq | |
Study Director: | abdulrrazaq S. Alsalman, phD | Babylon university/Iraq |
Responsible Party: | mahmoud hussein hadwan, phD, Babylon University |
ClinicalTrials.gov Identifier: | NCT01684059 |
Other Study ID Numbers: |
Babil-2 |
First Posted: | September 12, 2012 Key Record Dates |
Last Update Posted: | September 12, 2012 |
Last Verified: | September 2012 |
Asthenozoospermia Infertility, Male Infertility Zinc Sulfate |
Astringents Physiological Effects of Drugs Dermatologic Agents |