COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Safety and Efficacy of Endotracheal Intubation Using Glidescope Video-Laryngoscope

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01683526
Recruitment Status : Completed
First Posted : September 12, 2012
Results First Posted : June 25, 2014
Last Update Posted : October 20, 2014
Information provided by (Responsible Party):
Beth Israel Medical Center

Brief Summary:
The safety and efficacy of a video-laryngoscope as a primary intubation tool in urgent endotracheal intubation of critically-ill patients has not been well-described in the literature. This study will answer whether using a VL will impact on the efficacy and safety of intubation compared with a traditional direct laryngoscopy.

Condition or disease Intervention/treatment Phase
Respiratory Failure Procedure: Direct laryngoscopy Device: Video laryngoscopy (Glidescope) Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 117 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Safety and Efficacy of Endotracheal Intubation by Pulmonary Critical Care Physicians in Critically-Ill Patients Using Glidescope Video-Laryngoscope
Study Start Date : August 2012
Actual Primary Completion Date : April 2013
Actual Study Completion Date : April 2013

Arm Intervention/treatment
Active Comparator: Direct laryngoscopy
Intubation will be done using direct laryngoscopy
Procedure: Direct laryngoscopy
Other Name: standard laryngoscope

Active Comparator: Video laryngoscopy
Intubation will be done using video laryngoscopy
Device: Video laryngoscopy (Glidescope)
Other Name: Glidescope Video Laryngoscope

Primary Outcome Measures :
  1. First Pass Success Rate [ Time Frame: From begining of intubation to verification. Less then 5 minutes approximatly ]

Secondary Outcome Measures :
  1. Severe Desaturation [ Time Frame: For 10 minutes post intubation ]
    sat <80%

  2. Hypotension [ Time Frame: For 10 minutes post intubation ]

  3. Cardiac Arrest [ Time Frame: For 1 hour post intubation ]
  4. Complications of Intubation [ Time Frame: For 10 minutes post intubation ]
    Complications of intubation including aspiration, vomiting, esophageal intubation,and dental injury.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • All patients undergoing urgent endotracheal intubation by a pulmonary critical care medicine physician

Exclusion Criteria:

  • Difficult airway
  • Oxygen saturation < 92% despite adequate mask ventilation

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01683526

Layout table for location information
United States, New York
Beth Isreal Medical Center
New York, New York, United States, 10003
Sponsors and Collaborators
Beth Israel Medical Center
Layout table for investigator information
Principal Investigator: Michael Silverberg, MD Beth Israel Medical Center
Layout table for additonal information
Responsible Party: Beth Israel Medical Center Identifier: NCT01683526    
Other Study ID Numbers: 139-12
First Posted: September 12, 2012    Key Record Dates
Results First Posted: June 25, 2014
Last Update Posted: October 20, 2014
Last Verified: October 2014
Keywords provided by Beth Israel Medical Center:
Urgent endotrachel intubation
Direct laryngoscopy
Video laryngoscopy
Critical Care
Additional relevant MeSH terms:
Layout table for MeSH terms
Respiratory Insufficiency
Respiration Disorders
Respiratory Tract Diseases