Effect of High-calcium Intake on Appetite, Insulinemia and Incretins
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|ClinicalTrials.gov Identifier: NCT01682343|
Recruitment Status : Completed
First Posted : September 10, 2012
Last Update Posted : September 11, 2012
|Condition or disease||Intervention/treatment||Phase|
|Nutritional and Metabolic Diseases||Dietary Supplement: Calcium||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||10 participants|
|Intervention Model:||Crossover Assignment|
|Masking:||Double (Participant, Investigator)|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of High-calcium Intake on Appetite, Insulinemia and Incretins|
|Study Start Date :||May 2012|
|Actual Primary Completion Date :||August 2012|
|Actual Study Completion Date :||August 2012|
Placebo Comparator: Placebo
Breakfast consisting of milk-based porridge with a normal calcium content.
As control, but with a high-calcium content.
Dietary Supplement: Calcium
- Subjective appetite ratings [ Time Frame: 3 hour ]Subjective ratings of appetite assessed by visual analogue scales.
- Serum insulin concentration [ Time Frame: 2 hour ]2 hour area under the curve for serum insulin following breakfast consumption
- Plasma glucose-dependent insulinotropic peptide concentration [ Time Frame: 2 hour ]2 hour area under the curve for plasma glucose-dependent insulinotropic peptide following breakfast consumption
- Plasma glucagon-like peptide-1 concentration [ Time Frame: 2 hour ]2 hour area under the curve for plasma glucagon-like peptide-1 following breakfast consumption
- Total fat oxidised during 60 min of exercise (g) [ Time Frame: 1 hour ]Assessed by indirect calorimetry
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01682343
|Newcastle upon Tyne, Tyne on Wear, United Kingdom, NE1 8ST|
|Principal Investigator:||Javier T Gonzalez, MRes||Northumbria University|