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Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01680055
Recruitment Status : Withdrawn (No eligible patient was enrolled.)
First Posted : September 6, 2012
Last Update Posted : April 20, 2016
Information provided by (Responsible Party):
Ming Hou, Shandong University

Brief Summary:
This study is designed to collect bone marrow and/or peripheral blood cells and plasma, for the analysis of adhesion molecules, chemokines and their receptors from newly-diagnosed aplastic anemia patients, and patients treated with antithymocyte globulin plus cyclosporine

Condition or disease
Aplastic Anemia Healthy

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Study Type : Observational
Actual Enrollment : 0 participants
Observational Model: Case-Control
Time Perspective: Prospective
Study Start Date : February 2009
Estimated Study Completion Date : November 2012

Resource links provided by the National Library of Medicine

Acquired Aplastic Anemia Patients Treated with Antithymocyte Globulin plus Cyclosporine

Primary Outcome Measures :
  1. hematologic response [ Time Frame: 6 months following antithymocyte globulin plus cyclosporine treatment ]
    hematologic response at 6 months following antithymocyte globulin plus cyclosporine treatment, defined as no longer meeting the criteria for severe aplastic anemia

Information from the National Library of Medicine

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Ages Eligible for Study:   16 Years to 70 Years   (Child, Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients With Aplastic Anemia

Inclusion Criteria:

  • patients who fulfilled entry criteria of acquired aplastic anemia age range 16-70 years

Exclusion Criteria:

  • Patients complicated with diabetes, tumor, pregnancy, active infection, or connective tissue diseases, such as systemic lupus erythematosus.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01680055

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China, Shandong
Qilu Hospital, Shandong University
Jinan, Shandong, China, 250012
Sponsors and Collaborators
Shandong University
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Responsible Party: Ming Hou, Director, Shandong University Identifier: NCT01680055    
Other Study ID Numbers: Aplastic Anemia 1
First Posted: September 6, 2012    Key Record Dates
Last Update Posted: April 20, 2016
Last Verified: September 2012
Additional relevant MeSH terms:
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Anemia, Aplastic
Hematologic Diseases
Bone Marrow Diseases