Vibrational-proprioceptive Resistance Exercise Training Versus Neuromuscular Electrical Stimulation Training in Elderly People With Muscle Weakness (MOBIL)
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|ClinicalTrials.gov Identifier: NCT01679977|
Recruitment Status : Completed
First Posted : September 6, 2012
Last Update Posted : March 7, 2016
|Condition or disease||Intervention/treatment||Phase|
|Muscle Weakness Condition Therapy Effect||Device: Vibrational-proprioceptive Resistance Exercise Training Device: Neuromuscular Electrical Stimulation Training||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||150 participants|
|Intervention Model:||Factorial Assignment|
|Masking:||None (Open Label)|
|Study Start Date :||June 2008|
|Actual Primary Completion Date :||December 2014|
|Actual Study Completion Date :||March 2015|
Active Comparator: Legpress
Subjects in the LP group train on a custom built, computer controlled, linear electric motor powered leg press device. The so called "swinging" vibrational-proprioceptive mode is used, which means that constant velocity of the pedals (0.3 m/s and 0.2 m/s for concentric and eccentric phase, respectively) are interrupted by short stops (every 8 mm), resulting in short force peaks appearing throughout the movement. Training load is progressively increased throughout the training.
Device: Vibrational-proprioceptive Resistance Exercise Training
Active Comparator: E-Stim
ES training is performed with a custom-built battery-powered stimulator. The subject are seated over the edge of the therapeutic table with the trunk upright and lower legs freely swinging. Two conductive rubber electrodes covered by wet sponge are placed on the anterior thigh on each side of the body. The electrode pairs are connected to the independent channels of the stimulator and the left and the right thigh are stimulated in an alternative manner. Each repetition (i.e. ES evoked muscle contraction) is evoked by a 3.5 s train (60 Hz) of electrical pulses (rectangular, biphasic, width 0.6 ms). Consecutive contractions of the same thigh are separated by 4.5 s off intervals. Maximal tolerable intensity should be used and is monitored during the training sessions. In all the subjects this should induce a tetanic contraction of the stimulated muscles.
Device: Neuromuscular Electrical Stimulation Training
No Intervention: Control
This group only perform the same measurements as the intervention groups and lives their live as usual in between.
- Maximum voluntary knee extension torque [ Time Frame: pre Training, post Training, 3 months post training ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01679977
|Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation|
|Vienna, Austria, 1160|
|Facultiy of Physical Education and Sports, Comenius University of Bratislava|
|Bratislava, Slovakia, 81806|
|Study Chair:||Helmut Kern, MD PhD||Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation|