COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Assessment of Esophageal Motility With Transnasal Endoscopy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01658865
Recruitment Status : Unknown
Verified August 2012 by Myung-gui Choi, The Catholic University of Korea.
Recruitment status was:  Recruiting
First Posted : August 7, 2012
Last Update Posted : August 7, 2012
Information provided by (Responsible Party):
Myung-gui Choi, The Catholic University of Korea

Brief Summary:
The purpose of this study is to assese esophageal motor function by simplified transnasal endoscopy compared with esophageal manometry.

Condition or disease
Esophageal Motility Disorder

Detailed Description:

Esophageal manometry is a gold standard for diagnosis of esophageal motility disorder. However, esophageal manometry can not detect non-occulsive contraction. Endoscopic evaulation of esophageal motility is difficult becausea swallowing is nearly impossible during endoscopy. Simplified trans nasal endoscopy (E.G. ScanTM, IntroMedic Co.,Ltd.)composed with dysplay system,controller,and disposable probe with compact size.

The esophageal motor function will be assessed with both esophageal manometry and simplifed trnasnasal endoscopy in patients with esophageal motility disorder (such as achalasia) and healthy volunteer. The results of simplifed trnasnasal endoscopy is compared with the results of esophageal manometry.

Layout table for study information
Study Type : Observational
Estimated Enrollment : 40 participants
Observational Model: Case-Only
Time Perspective: Prospective
Study Start Date : July 2011
Estimated Primary Completion Date : September 2012
Estimated Study Completion Date : October 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Endoscopy

Transnasal endoscopy
Healthy volunteers and patients with esophageal motor symptom will be enrolled and esophageal motility assessed by transnasal endoscopy according to clinical and manometric diagnosis

Primary Outcome Measures :
  1. Agreement of endoscopic diagnosis of esophageal motor function with manometry [ Time Frame: one day ]

Secondary Outcome Measures :
  1. Discomfort of simplifed transnasal endoscopy compared with esophageal manomerty estimated by the patietns [ Time Frame: one day ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   18 Years to 70 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Patients with esophageal motility disorder Healthy volunteer

Inclusion Criteria:

  • 1) Healthy volunteer without organic esophageal or gastric disorder 2) Patients knwon esophageal motility disorder (such as achalasia)

Exclusion Criteria:

  • severe organic esophageal disorder including severe reflux esophagitis, stricture, and bleeding.
  • previous opertion of esophagus or stomach
  • GI bleeding, mechanical obstruction
  • medication which can infulence GI motility

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01658865

Layout table for location contacts
Contact: Myung-Gyu Choi, Prof. 82-2-2258-2044

Layout table for location information
Korea, Republic of
Seoul St. Mary's Hospital Recruiting
Seoul, Korea, Republic of
Contact: Myung-Gyu Choi, Prof    82-2-2258-2044   
Sponsors and Collaborators
The Catholic University of Korea
Layout table for additonal information
Responsible Party: Myung-gui Choi, prof., The Catholic University of Korea Identifier: NCT01658865    
Other Study ID Numbers: NE-EM-001
First Posted: August 7, 2012    Key Record Dates
Last Update Posted: August 7, 2012
Last Verified: August 2012
Additional relevant MeSH terms:
Layout table for MeSH terms
Esophageal Motility Disorders
Esophageal Spasm, Diffuse
Deglutition Disorders
Esophageal Diseases
Gastrointestinal Diseases
Digestive System Diseases