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Decrease the Frequency of Inappropriate Intravenous Lines in Internal Medicine (PERMI)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01633307
Recruitment Status : Completed
First Posted : July 4, 2012
Last Update Posted : July 4, 2012
Information provided by (Responsible Party):
Stephane Mouly, MD PhD, Hopital Lariboisière

Brief Summary:
Aim: to determine whether a nationwide teaching program delivered to medical doctors can decrease the use of inappropriate intravenous lines in internal medicine

Condition or disease Intervention/treatment Phase
Acute Medical Patients Hospitalized in Internal Medicine Other: Education Phase 4

Detailed Description:
Nationwide multicentre randomized prospective controlled trial enrolling 59 french internal medicine departments. During the first study visit, we collected data of patients with intravenous infusions from each participating centre in order to determine the number and frequency of inappropriate intravenous lines. Using a computerized randomization process (on a 1:1 basis), the participating centres were randomized; Half centres (interventional group) received an educational program consisting of educational material and two educational sessions; the other half did not receive the educational program (control group). The educational program provided medical doctors with posters and slides containing information on valid indications for the prescription and use of intravenous infusions (inability to drink or eat, malabsorption, medication only available intravenously with no oral equivalent). Based on a previous pilot study, we assumed that the the frequency of inappropriate intravenous lines with be approximately 20% at baseline and hypothesize that the nationwide teaching program will decrease this frequency by 50%.

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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 59 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Official Title: Effect of a Nationwide Teaching Program on the Frequency of Inappropriate Intravenous Lines in Internal Medicine: A Randomized Controlled Trial
Study Start Date : January 2007
Actual Primary Completion Date : April 2007
Actual Study Completion Date : May 2007

Arm Intervention/treatment
Experimental: Experimental
Intervention (Teaching program)
Other: Education
Teaching program

No Intervention: Control group
No teaching program

Primary Outcome Measures :
  1. frequency of inappropriate intravenous infusion in internal medicine department

Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Internal medicine department

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01633307

Sponsors and Collaborators
Hopital Lariboisière
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Principal Investigator: stephane J mouly, MD PhD Hopital Lariboisiere
Publications automatically indexed to this study by Identifier (NCT Number):
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Responsible Party: Stephane Mouly, MD PhD, Professor of Medicine, Hopital Lariboisière Identifier: NCT01633307    
Other Study ID Numbers: PERMI
First Posted: July 4, 2012    Key Record Dates
Last Update Posted: July 4, 2012
Last Verified: June 2012
Keywords provided by Stephane Mouly, MD PhD, Hopital Lariboisière:
intravenous infusion