Aspirin Twice Daily in Diabetic Patients With Coronary Artery Disease
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|ClinicalTrials.gov Identifier: NCT01617031|
Recruitment Status : Completed
First Posted : June 12, 2012
Last Update Posted : June 12, 2012
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||92 participants|
|Official Title:||Biological Efficacy of Twice Daily Aspirin in Type 2 Diabetic Patients With Coronary Artery Disease|
|Study Start Date :||September 2010|
|Actual Primary Completion Date :||March 2011|
|Actual Study Completion Date :||May 2012|
Diabetic patients with coronary artery disease
Type 2 diabetic patients with previous coronary artery disease. All patients are routinely treated with aspirin in secondary prevention of cardiovascular disease. Coronary artery disease is defined as a previous coronary angiography with at least 1 coronary artery stenosis >50%. Type 2 diabetes is defined as patients with diabetes discovered after 30 years old and insulin was not the first treatment except in case of acute coronary syndrome.
- Intensity of platelet agregation following exposure to 0.5 mg/ml arachidonic acid [ Time Frame: 10 days ]Flow cytometry study of the intensity of platelet agregation following exposure of Platelet reach plasma to 0.5 mg/ml arachidonic acid
- Closure time after exposure of total blood to Collagen-epinephrine [ Time Frame: 10 days ]Closure time after exposure of total blood to Collagen-epinephrine using Platelet Function Analyzer-100 (PFA-100) with collagen-epinephrine (EPI) cartridge.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01617031
|Department of Cardiology-Lariboisiere Hospital-Assistance Publique-Hôpitaux de Paris|
|Paris, France, 75010|
|Study Director:||Patrick Henry, MD-PhD||Assistance Publique - Hôpitaux de Paris|