Efficacy Of Copper To Reduce Acquisition Of Microbes and Healthcare-acquired Infections
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|ClinicalTrials.gov Identifier: NCT01565798|
Recruitment Status : Completed
First Posted : March 29, 2012
Last Update Posted : March 24, 2016
CONTEXT: Healthcare-acquired infections (HAI) cause substantial patient morbidity and mortality. Commonly touched items in the patient care environment harbor microorganisms that may contribute to HAI risk. Thus, reduction in the surface bioburden may be an effective strategy to reduce HAI. Inherent biocidal capabilities of copper surfaces offer a theoretical advantage to conventional cleaning, as disinfection is continuous rather than episodic.
OBJECTIVE: Determine whether placement of copper-alloy surfaced objects in an intensive care unit (ICU) reduce risk of HAI.
DESIGN: An intention to treat study where patients are sequentially placed into rooms with or without copper-alloy surfaced objects.
SETTING: The ICUs of three hospitals, a tertiary academic hospital, an academic cancer center, and a Veteran's Administration Medical Center.
PATIENTS: Any patient 18 years of age or older who required admission to an ICU at a study hospital is eligible for placement into a study room if available.
INTERVENTION: Placement of copper-alloy surfaced objects in an ICU room. MAIN OUTCOME MEASURE: Rate of incident HAI and/or colonization with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) in each type of room.
|Condition or disease||Intervention/treatment||Phase|
|Healthcare-acquired Infection||Other: Copper-alloy surfaced patient care objects||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||614 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Copper Antimicrobial Research Program: Environmental and Patient Sampling For Indicator Organisms To Determine The Efficacy Of Copper To Reduce Acquisition Of Microbes From The Patient Care Environment|
|Study Start Date :||July 2010|
|Actual Primary Completion Date :||June 2011|
|Actual Study Completion Date :||June 2011|
Experimental: Copper Surfaced Room
Patients sequentially randomized to this arm were admitted to an ICU room with copper surfaced objects.
Other: Copper-alloy surfaced patient care objects
Copper-alloy surfaced bed rails, over bed tray tables, chair arms, nurse call devices, laptop and computer monitor bezels, and IV poles were placed into the patient ICU rooms.
No Intervention: Standard Surfaced Room
Patients sequentially randomized to this arm were admitted to an ICU room with standard surfaced objects
- Rate of incident HAI and/or colonization with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) in each type of room. [ Time Frame: July 2010 to June 2011 (up to 1 year) ]Patients prospectively followed from ICU admission to hospital discharge for acquisition of HAI and/or colonization with MRSA or VRE
- Microbial burden and risk of HAI [ Time Frame: July 2010 to June 2011 (up to 1 year) ]The risk of HAI among patients admitted to ICU will be assessed by microbial burden of environment.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01565798
|United States, South Carolina|
|Medical University of South Carolina|
|Charleston, South Carolina, United States, 29425|
|Principal Investigator:||Michael G Schmidt, PhD||Medical University of South Carolina|