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Analysis of Percutaneous Ablations for Cancer Treatment

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01563679
Recruitment Status : Completed
First Posted : March 27, 2012
Last Update Posted : May 28, 2014
Information provided by (Responsible Party):
Hyun Kevin Kim, Emory University

Brief Summary:

This is a study involving patients with cancer who are referred by their treating physician for percutaneous locoregional therapies.

Patient's clinical and radiology findings, pathology findings, survival, treatment responses, and complications after their locoregional therapy will be studied.

Condition or disease

Detailed Description:

The efficacy of the percutaneous and transarterial treatments for solid tumors will be studied. Prospective study on patients who receive percutaneous locoregional therapies, including radiofrequency ablation (RFA), cryoablation, microwave ablation, IRE and chemical ablation for treatment of cancer will be performed.

Preoperative clinic chart, procedure note, postoperative chart, pre- and post-operative CT, MRI or Ultrasound, angiographic findings, biopsy results and pathologic findings, will be reviewed. Patient survival, treatment responses, complications after the therapy will be collected from clinic visits and clinical encounters.

Patient overall performance status before and after procedures will be assessed using the Quality of Life questionnaire (SF-36™ Health Survey).

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Study Type : Observational
Actual Enrollment : 26 participants
Time Perspective: Prospective
Official Title: Prospective Analysis of Percutaneous Ablations for Cancer Treatment
Study Start Date : February 2012
Actual Primary Completion Date : January 2014
Actual Study Completion Date : January 2014

Primary Outcome Measures :
  1. Effect of percutaneous and transarterial treatments for cancer in quality of life [ Time Frame: 1 year ]
    Patients will complete the QOL questionnare during their follow up visits after procedure. 1 month, 3 months, 6 months and 1 year.

Secondary Outcome Measures :
  1. response rate to percutaneous and transarterial treatment for cancer [ Time Frame: 1 month, 3 months, 6 months, 1 year. ]
    Patients will be followed up 1, 3, 6 and 1year intervals after procedure.

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients who undergo ablative therapy procedures, in the Interventional Radiology department as part of a clinical treatment for cancer.

Inclusion Criteria:

  • 18yrs of age
  • Cancer diagnosis
  • Candidate for Locoregional therapy
  • Willingness to sign informed consent

Exclusion Criteria:

  • Unable to sign informed consent
  • Patients not eligible for locoregional therapies

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01563679

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United States, Georgia
Emory University Hospital
Altanta, Georgia, United States, 30322
Sponsors and Collaborators
Emory University
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Principal Investigator: Hyun S Kim, MD Emory University
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Responsible Party: Hyun Kevin Kim, Director of Interventional Radiology and Image-guided Medicine, Emory University Identifier: NCT01563679    
Other Study ID Numbers: IRB00054905
RAD2160-11 ( Other Identifier: Other )
First Posted: March 27, 2012    Key Record Dates
Last Update Posted: May 28, 2014
Last Verified: May 2014
Keywords provided by Hyun Kevin Kim, Emory University:
locoregional therapies
Microwave ablation
chemical ablation
Irreversible electroporation