COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Gender-specific aEEGs and Outcome in Preterms

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01562236
Recruitment Status : Completed
First Posted : March 23, 2012
Last Update Posted : March 23, 2012
Information provided by (Responsible Party):
Monika Olischar, Medical University of Vienna

Brief Summary:

Background and objectives: Male sex is a risk factor for poor neurodevelopmental outcome following preterm birth. The investigators aimed to investigate gender-related differences in amplitude-integrated electroencephalography (aEEG) and to correlate these findings with neurodevelopmental outcome.

Methods: Preterm infants born <30 weeks' gestational age between 2000 and 2002 were prospectively included. aEEGs obtained within the first two weeks of life were evaluated and classified according to background activity, sleep-wake cycling (SWC) and seizure activity. Outcome was assessed at three years.

Condition or disease
Gender Role Disorder, Male to Female Type

Layout table for study information
Study Type : Observational
Actual Enrollment : 148 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Gender-related Differences in Early Amplitude-integrated Electroencephalography in Newborns < 30 Weeks' Gestational Age and Their Correlation With Neurodevelopment Outcome at Three Years Corrected Age
Study Start Date : January 2000
Actual Primary Completion Date : December 2002
Actual Study Completion Date : October 2011

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   24 Weeks to 30 Weeks   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
preterms born < 30 weeks gestational age who had aEEG measurements within the first 2 weeks of life who had assessment of outcome at 3 years corrected age

Inclusion Criteria:

  • born<30 weeks gestational age
  • who had aEEGs in first 2 weeks of life
  • who were assessed for outcome at 3 years of age

Exclusion Criteria:

  • born>30 weeks gestational age
  • had no aEEGs in first 2 weeks of life
  • lost for follow-up at 3 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01562236

Layout table for location information
Medical University of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
Layout table for investigator information
Principal Investigator: Monika Olischar, MD Neonatology
Layout table for additonal information
Responsible Party: Monika Olischar, Ass Prof Dr, Medical University of Vienna Identifier: NCT01562236    
Other Study ID Numbers: gender148
First Posted: March 23, 2012    Key Record Dates
Last Update Posted: March 23, 2012
Last Verified: March 2012