Minimally Invasive Radioguided Parathyroidectomy (MIRP)
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ClinicalTrials.gov Identifier: NCT01530919 |
Recruitment Status :
Completed
First Posted : February 10, 2012
Last Update Posted : May 4, 2017
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Condition or disease | Intervention/treatment |
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Primary Hyperparathyroidism | Procedure: Minimally invasive radioguided parathyroidectomy |
Study Type : | Observational |
Actual Enrollment : | 856 participants |
Observational Model: | Cohort |
Time Perspective: | Cross-Sectional |
Official Title: | Minimally Invasive Radioguided Parathyroidectomy |
Study Start Date : | September 1998 |
Actual Primary Completion Date : | December 2009 |
Actual Study Completion Date : | April 2017 |

Group/Cohort | Intervention/treatment |
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Parathyroid surgery
Database of patients who have undergone minimally invasive radioguided parathyroidectomy
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Procedure: Minimally invasive radioguided parathyroidectomy
After the patient is prepared for surgery and under local anesthesia, the initial incision by the surgeon will be 2-3 cm. The surgeon will dissect in the designated quadrant until the parathyroid gland is identified. |
- The positive and negative predictive value of sestamibi scanning to detect parathyroid adenomas. [ Time Frame: 2-3days ]
- The value of intraoperative parathyroid hormone assay to verify biochemical cure or primary hyperparathyroidism [ Time Frame: 2-3 days ]
- Collection of abnormal parathyroid tissue at the time of surgery for tissue analysis [ Time Frame: day of surgery (1 day) ]
Biospecimen Retention: Samples With DNA

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Ages Eligible for Study: | Child, Adult, Older Adult |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- All patients with biochemical evidence of primary hyperparathyroidism

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01530919
United States, Kentucky | |
University of Louisville | |
Louisville, Kentucky, United States, 40202 |
Principal Investigator: | Michael J Flynn, M.D. | University of Louisville |
Responsible Party: | Michael B. Flynn, MD, Professor, University of Louisville |
ClinicalTrials.gov Identifier: | NCT01530919 |
Other Study ID Numbers: |
291.97 |
First Posted: | February 10, 2012 Key Record Dates |
Last Update Posted: | May 4, 2017 |
Last Verified: | May 2017 |
Hyperparathyroidism Hyperparathyroidism, Primary Parathyroid Diseases Endocrine System Diseases |